{"id":"W4229033811","doi":"10.1172/jci.insight.157811","title":"The innate immune response following multivalent dengue vaccination and implications for protection against dengue challenge","year":2022,"lang":"en","type":"article","venue":"JCI Insight","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Population and Public Health","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Dengue vaccine; Dengue fever; Immune system; Vaccination; Dengue virus; Immunology; Innate immune system; Immunity; Medicine; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000533762,0.0001176443,0.0001517842,0.00009029745,0.001044854,0.00003678611,0.00009275976,0.00004116574,0.00001137815],"category_scores_gemma":[0.0003714506,0.00009173241,0.0001486236,0.0001560591,0.00001182358,0.00005931744,0.00008523092,0.0001672458,0.000001667928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001444884,"about_ca_system_score_gemma":0.00008932617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001653545,"about_ca_topic_score_gemma":0.00001815527,"domain_scores_codex":[0.9989677,0.0001677808,0.0002456993,0.0002609796,0.0001616574,0.0001961829],"domain_scores_gemma":[0.9991955,0.0001865635,0.0001035568,0.0003366657,0.0001019386,0.00007580053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.009917039,0.001475978,0.003345742,0.0002663672,0.0007740862,0.00003981325,0.004673755,0.0002201882,0.3697036,0.007846636,0.001754172,0.5999826],"study_design_scores_gemma":[0.008609466,0.001059392,0.6800542,0.00005860733,0.0003278167,0.00002770576,0.001573806,0.008824659,0.002387087,0.000852015,0.2958847,0.0003405154],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9688458,0.007983305,0.001132463,0.01832449,0.000337647,0.003008956,0.00003468066,0.00007675876,0.0002558334],"genre_scores_gemma":[0.9949739,0.000245099,0.00004558581,0.0002604562,0.0001280275,0.003491614,0.00004552292,0.0000277431,0.0007820624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6767085,"threshold_uncertainty_score":0.8036277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02402207697920138,"score_gpt":0.2916964442545417,"score_spread":0.2676743672753403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}