{"id":"W4229043691","doi":"10.1101/2022.05.04.22274088","title":"Major Depressive Disorder as a risk factor of neuropsychiatric symptoms in normal and pathological aging, and associations with cognitive performances","year":2022,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Treatment of Major Depression","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec; Université de Montréal; Institut Universitaire de Gériatrie de Montréal","funders":"Fonds de Recherche du Québec - Santé; Parkinson Canada; National Institute on Aging; National Institutes of Health; Université de Montréal","keywords":"Major depressive disorder; Depression (economics); Logistic regression; Cognition; Psychology; Clinical psychology; Pathological; Effects of sleep deprivation on cognitive performance; Risk factor; Psychiatry; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005124496,0.0002603974,0.0002508321,0.000554495,0.0002277806,0.0004447499,0.0001977099,0.0002620629,0.0008668223],"category_scores_gemma":[0.001380031,0.0001477452,0.0004480793,0.0004036847,0.0001613743,0.0001695087,0.000270645,0.0003213857,0.00009740143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001771909,"about_ca_system_score_gemma":0.0001442286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003302358,"about_ca_topic_score_gemma":0.005118042,"domain_scores_codex":[0.9997848,0.00006209426,0.00003796311,0.00005522714,0.00003014837,0.00002972325],"domain_scores_gemma":[0.9993184,0.0001182069,0.0003132953,0.00005035388,0.0000646196,0.0001351923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001161656,0.0000170212,0.9987605,0.000007136773,0.00007452285,0.00004022922,0.00001876527,0.00001460481,0.0001349471,0.00001061406,0.00004452166,0.0007609215],"study_design_scores_gemma":[0.000002638643,0.00002443472,0.999726,0.000001763352,0.00002374124,0.00007956717,0.00002180344,0.00006451176,0.00001620231,0.00001220601,0.00002660045,5.971326e-7],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988332,0.0005882144,0.00006204096,0.00002993902,0.000008830601,0.000005043314,0.0002020429,0.000002046381,0.0002685644],"genre_scores_gemma":[0.9996374,0.00007894941,0.0000464039,0.000007750759,0.000007977912,0.000002451271,0.0001582604,4.402279e-7,0.00006039911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003302358,"threshold_uncertainty_score":0.006566286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01077397331726174,"score_gpt":0.2712647087401516,"score_spread":0.2604907354228898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}