{"id":"W4229048491","doi":"10.1371/journal.pone.0266181","title":"Efficient gene transfection to lung cancer cells via Folate-PEI-Sorbitol gene transporter","year":2022,"lang":"en","type":"article","venue":"PLoS ONE","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Transfection; Cancer cell; Apoptosis; Gene delivery; Cancer research; Lung cancer; Cancer; Gene silencing; Genetic enhancement; Cytotoxicity; In vivo; Biology; Chemistry; Cell biology; In vitro; Biochemistry; Medicine; Gene; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002400883,0.0003231101,0.0003913754,0.000200357,0.000193833,0.0002966566,0.0002851626,0.0004582642,0.0007380933],"category_scores_gemma":[0.0001376594,0.0001472226,0.0002971754,0.0003139668,0.0002290573,0.0002844021,0.0002329634,0.0004797991,0.000379485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003925908,"about_ca_system_score_gemma":0.0003072822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001250685,"about_ca_topic_score_gemma":0.001376259,"domain_scores_codex":[0.999816,0.00003142437,0.00001915314,0.00005017685,0.00004949523,0.00003380403],"domain_scores_gemma":[0.999958,0.000009923364,0.00001126275,0.000005413918,0.000008890938,0.000006495228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003336329,0.00001249141,0.00005218203,0.00005829826,0.000004323424,0.00006686376,0.00003811483,0.0001298496,0.9978934,0.0002691256,0.00005180983,0.001390196],"study_design_scores_gemma":[0.00001563499,0.0001781748,0.0003590079,0.000004765757,0.00001232683,0.0001514948,0.00001557763,0.002059904,0.9922719,0.00003847123,0.00488701,0.000005822179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9428801,0.00288213,0.04877557,0.000300398,0.00009585469,0.0003205539,0.0006370892,0.0003241668,0.003784167],"genre_scores_gemma":[0.9616795,0.002122898,0.02732481,0.00008527379,0.00001408272,0.0002345399,0.0007605238,0.00005310948,0.007725155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001250685,"threshold_uncertainty_score":0.002848446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01370514971024981,"score_gpt":0.2207663903794259,"score_spread":0.2070612406691761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}