{"id":"W4229063410","doi":"10.1016/j.jcjo.2022.04.005","title":"OCTA changes following loading phase with intravitreal aflibercept for DME","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Ophthalmology","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan; Saskatoon City Hospital","funders":"","keywords":"Medicine; Aflibercept; Diabetic retinopathy; Ophthalmology; Visual acuity; Ranibizumab; Prospective cohort study; Optical coherence tomography angiography; Macular edema; Diabetes mellitus; Bevacizumab; Optical coherence tomography; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001267895,0.0002005608,0.0003552831,0.0003229878,0.000207682,0.000433856,0.0001515418,0.0003537494,0.002753082],"category_scores_gemma":[0.0007318172,0.0000824926,0.0002246099,0.0002740374,0.0001775031,0.0003823114,0.0001233959,0.0007546641,0.0004387573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003416582,"about_ca_system_score_gemma":0.0003488955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002498292,"about_ca_topic_score_gemma":0.003911532,"domain_scores_codex":[0.9998273,0.00001911584,0.00001019465,0.00002150845,0.00005479311,0.00006702772],"domain_scores_gemma":[0.999691,0.0000762692,0.00005707583,0.00001928796,0.00007805323,0.00007829053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.09975025,0.005408579,0.0249134,0.0003254099,0.0001770678,0.004179906,0.0004955386,0.0005891313,0.7035282,0.0002818293,0.004024317,0.1563264],"study_design_scores_gemma":[0.002230439,0.02803876,0.4774962,0.0001261951,0.0007147639,0.006841578,0.001389937,0.007358277,0.4511118,0.0009984829,0.02350657,0.0001870185],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926425,0.00125056,0.0005250434,0.0001951104,0.0001695085,0.00008756128,0.0004610296,0.00006573214,0.004603016],"genre_scores_gemma":[0.996748,0.0003438132,0.000365959,0.0001584115,0.00005388961,0.00004804899,0.000340211,0.0000175184,0.00192413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002753082,"threshold_uncertainty_score":0.009209991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03164049596785736,"score_gpt":0.3222445698112158,"score_spread":0.2906040738433585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}