{"id":"W4229064793","doi":"10.1038/s41598-022-11634-6","title":"Investigation of role of CpG methylation in some epithelial mesenchymal transition gene in a chemoresistant ovarian cancer cell line","year":2022,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Technische Universität München; Concordia University","keywords":"DNA methylation; CpG site; Methylation; Epithelial–mesenchymal transition; Cancer research; Biology; Bisulfite sequencing; Cisplatin; Epigenetics; Ovarian cancer; Molecular biology; Gene expression; Cancer; Gene; Genetics; Transition (genetics); Chemotherapy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000112892,0.0001324018,0.0002410282,0.0003268079,0.000223515,0.000168604,0.000112983,0.0002251474,0.001263863],"category_scores_gemma":[0.0001376012,0.0001220414,0.0002095851,0.0004000695,0.0001174669,0.00009970017,0.00009524801,0.0003698633,0.000326725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000170429,"about_ca_system_score_gemma":0.0001846551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001727819,"about_ca_topic_score_gemma":0.002366058,"domain_scores_codex":[0.9998535,0.00001611199,0.00001562324,0.00004042879,0.00005827989,0.00001603168],"domain_scores_gemma":[0.999898,0.00002098368,0.00001995353,0.0000172128,0.00003190299,0.00001201239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003585617,0.00002112887,0.0007798211,0.00003048767,0.0000052305,0.0000480909,0.00004502624,0.00004115963,0.9978656,0.00003804485,0.00005822379,0.001031348],"study_design_scores_gemma":[0.0000116245,0.0004939355,0.02959427,0.00000720196,0.00004008994,0.0004446893,0.0001087111,0.001104083,0.9633675,0.00005673518,0.004763293,0.000007912749],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893489,0.001378949,0.004438683,0.0001378525,0.00003234674,0.00007352545,0.002341884,0.00008609935,0.002161887],"genre_scores_gemma":[0.9777164,0.001798313,0.007895179,0.0001604122,0.00001273737,0.0002331508,0.006330836,0.00002659162,0.005826452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001727819,"threshold_uncertainty_score":0.004227996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01092433286659246,"score_gpt":0.2376056077143449,"score_spread":0.2266812748477524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}