{"id":"W4229333219","doi":"10.14740/jmc3918","title":"Survival Benefit of Pembrolizumab for Patients With Pancreatic Adenocarcinoma: A Case Series","year":2022,"lang":"en","type":"article","venue":"Journal of Medical Cases","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Pembrolizumab; FOLFIRINOX; Gemcitabine; Oncology; Irinotecan; Olaparib; Internal medicine; Pancreatic cancer; Chemotherapy; Cancer; Immunotherapy; Colorectal cancer; Poly ADP ribose polymerase","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001069675,0.0001196331,0.000819343,0.0001787477,0.0001560339,0.000005703423,0.0001626576,0.00007604025,0.001352516],"category_scores_gemma":[0.001954974,0.00007858587,0.0001520183,0.0001832823,0.0002266334,0.0000693074,0.00008980512,0.0004416444,6.989809e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000131953,"about_ca_system_score_gemma":0.001068379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008483235,"about_ca_topic_score_gemma":0.00003527106,"domain_scores_codex":[0.997053,0.0001277427,0.0006129935,0.0001212798,0.001827544,0.0002574039],"domain_scores_gemma":[0.9974023,0.001162788,0.0003586253,0.0001623277,0.0005195583,0.0003943695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"case_report","study_design_scores_codex":[0.0139607,0.001482632,0.9459097,0.0004173586,0.0005138502,0.03220565,0.0004044104,0.000004567417,0.0000085407,0.000407087,0.002717964,0.001967581],"study_design_scores_gemma":[0.04999889,0.08267608,0.4182098,0.0006710113,0.003241741,0.4291405,0.008723129,0.0004778668,0.00007681259,0.0004823146,0.005953897,0.0003479663],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962009,0.0009516405,0.0001071811,0.001979668,0.0001536605,0.0003617296,0.00007125751,0.000005276247,0.0001686395],"genre_scores_gemma":[0.9983163,0.00008152143,0.0008624207,0.0001470788,0.0002114313,0.00003416908,0.00001419841,0.0000182947,0.0003145256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5276998,"threshold_uncertainty_score":0.9995604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03598566853732795,"score_gpt":0.3317811058234291,"score_spread":0.2957954372861012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}