{"id":"W4229442567","doi":"10.1183/23120541.lsc-2022.123","title":"Regulation of MHC I expression in lung epithelial cells during inflammation.","year":2022,"lang":"en","type":"article","venue":"","topic":"Pediatric health and respiratory diseases","field":"Health Professions","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Downregulation and upregulation; Inflammation; Alveolar Epithelium; Lung; Respiratory epithelium; Immunology; Major histocompatibility complex; Biology; Immune system; Cell biology; MHC class I; Cytokine; Epithelium; MHC class II; Antigen presentation; Bronchoalveolar lavage; Medicine; T cell; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000127057,0.0001821872,0.0001626779,0.0002069435,0.0001409977,0.0002472444,0.00009217144,0.0002054019,0.00106458],"category_scores_gemma":[0.00008793622,0.00009283026,0.0001963786,0.0001368486,0.0002133264,0.0001753129,0.0001695707,0.0003603593,0.0004129841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001793145,"about_ca_system_score_gemma":0.00009815938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002180582,"about_ca_topic_score_gemma":0.0002773783,"domain_scores_codex":[0.9998419,0.00002744901,0.00001114572,0.00004115617,0.00003027537,0.00004800762],"domain_scores_gemma":[0.9999022,0.00001602002,0.00002626072,0.000007445299,0.00002069569,0.00002729865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004562607,0.000003851167,0.000246835,0.00001414488,0.000001035725,0.00001705613,0.000009226002,0.000004898874,0.9993099,0.00001210399,0.000008068101,0.0003272654],"study_design_scores_gemma":[0.00001515071,0.0004446679,0.07632203,0.00002458603,0.0000270404,0.0003736838,0.0001973891,0.0005571648,0.9191902,0.0001062052,0.002734211,0.000007689673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913285,0.003802018,0.002277096,0.0001094383,0.00005613042,0.00003038956,0.0005754951,0.00004060562,0.001780309],"genre_scores_gemma":[0.9935527,0.001356888,0.001955853,0.0001165221,0.00003243353,0.0000581587,0.0006997408,0.0000143334,0.002213441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00106458,"threshold_uncertainty_score":0.003561318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02230535372736856,"score_gpt":0.3486219853316678,"score_spread":0.3263166316042992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}