{"id":"W4229615272","doi":"10.1002/ange.201506312","title":"Binding‐Induced DNA Nanomachines Triggered by Proteins and Nucleic Acids","year":2015,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates; Alberta Health; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Oligonucleotide; DNA; Nucleic acid; Biophysics; Aptamer; Chemistry; DNA nanotechnology; Ligand (biochemistry); Nanotechnology; Combinatorial chemistry; Biochemistry; Biology; Materials science; Molecular biology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001481042,0.0002459703,0.0001871669,0.0001358047,0.000144689,0.0002512426,0.0003298441,0.0003452275,0.001246623],"category_scores_gemma":[0.0002685958,0.0001840308,0.000153276,0.00007943897,0.0004647798,0.0003453608,0.0003412724,0.0005297826,0.0003357044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003111167,"about_ca_system_score_gemma":0.0001584692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001859756,"about_ca_topic_score_gemma":0.0002786041,"domain_scores_codex":[0.999828,0.00002363103,0.000007283137,0.00003918303,0.00007260803,0.00002937395],"domain_scores_gemma":[0.9998705,0.00005537999,0.000023763,0.00001234065,0.00001625426,0.000021849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002137405,0.000006017093,0.0000476671,0.00002373295,0.000001634163,0.00003858017,0.00002073284,0.0001553169,0.9980633,0.0004325287,0.00004567039,0.001143323],"study_design_scores_gemma":[0.000008682096,0.00004684683,0.0002498151,0.000001544184,0.000001459254,0.00006386669,0.000008482876,0.001188957,0.9962085,0.0001434142,0.002073582,0.000004844298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9302656,0.002139939,0.05885949,0.0003622817,0.0002275002,0.00008038861,0.0001284355,0.0005773927,0.007358963],"genre_scores_gemma":[0.979441,0.0003872382,0.01604916,0.0001383965,0.00002524284,0.00005099593,0.00005681959,0.00002763773,0.003823454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001246623,"threshold_uncertainty_score":0.004170418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01794256805268303,"score_gpt":0.2657457098297072,"score_spread":0.2478031417770242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}