{"id":"W4229985769","doi":"10.3410/f.736524765.793577580","title":"Faculty Opinions recommendation of Oral 5-azacytidine and romidepsin exhibit marked activity in patients with PTCL: a multicenter phase 1 study.","year":2020,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Romidepsin; Medicine; Phase (matter); Internal medicine; Chemistry; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001755081,0.00129873,0.001762902,0.001173387,0.0005068569,0.001734323,0.002925609,0.00211765,0.03402081],"category_scores_gemma":[0.0100631,0.0005236579,0.001975012,0.002273006,0.0002536067,0.0007925798,0.001285909,0.001364135,0.01522503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001581279,"about_ca_system_score_gemma":0.00333063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01394375,"about_ca_topic_score_gemma":0.03435969,"domain_scores_codex":[0.9988768,0.0002841367,0.0001695766,0.0003208738,0.0002261124,0.0001224969],"domain_scores_gemma":[0.9967686,0.001153355,0.0006974075,0.0004777911,0.0004956592,0.0004072425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.003288531,0.0001403761,0.009120977,0.004702688,0.0009317429,0.00007262597,0.00002329759,0.0007921563,0.0003931117,0.0004264148,0.9659847,0.01412333],"study_design_scores_gemma":[0.0223547,0.0005560141,0.08257652,0.003966515,0.003416296,0.0006829184,0.0001251105,0.003480865,0.002194677,0.003396959,0.8770868,0.000162624],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.001079746,0.0003472432,0.00007834066,0.0001893657,0.00002478405,0.00004836925,0.9973308,0.0001147999,0.000786534],"genre_scores_gemma":[0.003744995,0.0002741151,0.0004636122,0.0002807649,0.00001892829,0.0003598731,0.993811,0.00004475741,0.00100204],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.03402081,"threshold_uncertainty_score":0.113811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02298823500229985,"score_gpt":0.3490794127369473,"score_spread":0.3260911777346474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}