{"id":"W4229991244","doi":"10.1158/1538-7445.compsysbio-pr14","title":"Abstract PR14: Integrative functional genomics of breast cancer","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Gene expression and cancer classification","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre","funders":"","keywords":"Synthetic lethality; Druggability; Small hairpin RNA; Breast cancer; Cancer; Biology; Epigenetics; Somatic cell; Cancer research; Gene; Genomics; Computational biology; Copy-number variation; Functional genomics; Drug discovery; Genetics; Genome; Bioinformatics; Gene knockdown; DNA repair","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001631254,0.001139433,0.001013071,0.0009372798,0.0002689253,0.0005923496,0.001159336,0.00040367,0.003939621],"category_scores_gemma":[0.00066111,0.0004251301,0.001316818,0.0008061854,0.0002772453,0.0002925425,0.0007203076,0.0009780965,0.001110409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006923905,"about_ca_system_score_gemma":0.0009916036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002359056,"about_ca_topic_score_gemma":0.003563473,"domain_scores_codex":[0.9992975,0.000207944,0.00003153194,0.0001961542,0.0002030177,0.00006387498],"domain_scores_gemma":[0.999728,0.0001196385,0.00005110621,0.00003548291,0.00003785185,0.00002776541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008786821,0.0003979926,0.006484535,0.0008572709,0.0005293118,0.0002534003,0.000111363,0.05882907,0.7893165,0.01900967,0.009663554,0.1136688],"study_design_scores_gemma":[0.0003547775,0.001530748,0.02178259,0.00007326672,0.0004926888,0.000672693,0.00007409107,0.6075909,0.2719873,0.01074818,0.08454688,0.0001459433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1573577,0.001669679,0.7949626,0.0005890768,0.0002154279,0.0005327011,0.02342754,0.01275485,0.008490515],"genre_scores_gemma":[0.3520991,0.001552483,0.592986,0.0004421382,0.00009289436,0.001080374,0.03885476,0.003233847,0.009658514],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003939621,"threshold_uncertainty_score":0.01317936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1167201423048374,"score_gpt":0.4073725236033889,"score_spread":0.2906523812985514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}