{"id":"W4230387229","doi":"10.1002/1521-4141(200002)30:2<423::aid-immu423>3.3.co;2-s","title":"A subunit vaccine candidate region of the Entamoeba histolytica galactose-adherence lectin promotes interleukin-12 gene transcription and protein production in human macrophages","year":2000,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Medical Research Council Canada; McGill University","keywords":"Entamoeba histolytica; Biology; Lectin; Molecular biology; Protein subunit; Mannan-binding lectin; Immune system; C-type lectin; Microbiology; Gene; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008039783,0.000189258,0.0001655516,0.00007304369,0.00007491342,0.0001582706,0.00005511397,0.0001442501,0.0008290795],"category_scores_gemma":[0.00008027633,0.00007056743,0.0001178738,0.00006591,0.0000853203,0.00007351537,0.0001210896,0.0003191829,0.0002789922],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007509917,"about_ca_system_score_gemma":0.000115155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001653331,"about_ca_topic_score_gemma":0.0002046296,"domain_scores_codex":[0.9999471,0.00001361145,0.000004460162,0.000008611186,0.00001070601,0.00001557198],"domain_scores_gemma":[0.999977,0.000005567023,0.000003723931,0.000002838242,0.000004000655,0.000006806965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001817899,0.00005481394,0.0001035186,0.00001721271,0.000001719083,0.00002558113,0.000009009302,0.00001894415,0.9986414,0.00001535306,0.00001825159,0.0009123302],"study_design_scores_gemma":[0.00009302417,0.001810082,0.007370406,0.00001043766,0.00002911656,0.0002852118,0.00004453514,0.0007657935,0.9865085,0.00005834927,0.003021081,0.000003463245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977319,0.0007054193,0.000855497,0.00004058666,0.00001595532,0.00002462828,0.00007344713,0.00001429597,0.0005382582],"genre_scores_gemma":[0.9972831,0.0004740677,0.0009251554,0.00003509949,0.000009129089,0.00002934084,0.0002403739,0.000004051615,0.0009995876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008290795,"threshold_uncertainty_score":0.002773523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0141116001749304,"score_gpt":0.2326650669825565,"score_spread":0.2185534668076261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}