{"id":"W4230558340","doi":"10.1016/j.jcjd.2013.11.003","title":"Epidermal Growth Factor Signalling Promotes Pancreatic Beta-Cell Proliferation in Response to Nutrient Excess in Rats Through MTOR And FOXM1","year":2013,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Endocrinology; Internal medicine; Epidermal growth factor; PI3K/AKT/mTOR pathway; Growth factor; Insulin resistance; Beta cell; Insulin; Cell growth; Transcription factor; Receptor; Medicine; Islet; Insulin-like growth factor; Biology; Signal transduction; Cell biology; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000245134,0.0008294521,0.000701302,0.000960719,0.0004456666,0.0006346581,0.0004543774,0.000564215,0.002958861],"category_scores_gemma":[0.0002720049,0.0005310301,0.0006934303,0.0003561353,0.001109309,0.0007354169,0.0004894303,0.00187502,0.0004030598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009802422,"about_ca_system_score_gemma":0.0009013235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003931172,"about_ca_topic_score_gemma":0.005794909,"domain_scores_codex":[0.9997178,0.00002876063,0.00001894855,0.00006596823,0.00006254653,0.0001059897],"domain_scores_gemma":[0.9996319,0.00002442317,0.0001107736,0.00003657608,0.00003000746,0.0001662657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01213164,0.0002636216,0.00188595,0.0001040295,0.00004671637,0.0002490842,0.00006187237,0.0001036446,0.9785568,0.0003061134,0.0002327362,0.006057751],"study_design_scores_gemma":[0.0005237277,0.002219168,0.04344825,0.0000410583,0.0002893939,0.0003954816,0.0005779699,0.001404797,0.9467356,0.0006532841,0.003650807,0.00006047917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963303,0.00130496,0.000733713,0.000331425,0.0000660361,0.00001032112,0.0002873479,0.0001018861,0.0008340626],"genre_scores_gemma":[0.9922099,0.001143781,0.001250934,0.0001878467,0.00003501434,0.00006351444,0.0003452353,0.00008699811,0.004676701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003931172,"threshold_uncertainty_score":0.009898365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0192678907510252,"score_gpt":0.2359237705003302,"score_spread":0.216655879749305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}