{"id":"W4230721068","doi":"10.1182/blood.v96.13.4185.h8004185_4185_4193","title":"Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G2/M transit and do not reenter G0","year":2000,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":212,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Stem cell; Haematopoiesis; Biology; Stem cell factor; Cell biology; Cord blood; Population; CD34; Interleukin 3; Homing (biology); Progenitor cell; Molecular biology; Cell cycle; Immunology; Cell; T cell; Antigen-presenting cell; Medicine; Biochemistry; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001779566,0.0002744622,0.0004417452,0.0001698596,0.00008418993,0.00004529328,0.00008224623,0.0001254269,0.0002429748],"category_scores_gemma":[0.000001107286,0.0002407286,0.00008102821,0.0001831383,0.00003260391,0.00006440304,0.0000133869,0.0001975329,0.00007279176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000374947,"about_ca_system_score_gemma":0.00002635976,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001934414,"about_ca_topic_score_gemma":0.000005969992,"domain_scores_codex":[0.9982428,0.00008211719,0.0005046899,0.0004688874,0.0002994483,0.0004020384],"domain_scores_gemma":[0.9993562,0.00002189125,0.00004205107,0.0003027773,0.00003677004,0.0002403461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008938505,0.0007936716,0.0008487813,0.0006233679,0.0001081752,0.0006590777,0.004837729,0.0001776835,0.9903283,0.000004220303,0.000005154189,0.0007200593],"study_design_scores_gemma":[0.01077113,0.0002556682,0.01082285,0.000525772,0.0002434822,0.000382001,0.0001822716,0.0001319738,0.9764016,0.00001069507,0.00002767317,0.0002448942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997713,0.0001142915,0.0000641321,0.0003061027,0.00003777259,0.001333519,0.0000324852,0.00008576288,0.0003129263],"genre_scores_gemma":[0.9987016,0.00003395939,0.0002510455,0.0002060663,0.00006280626,0.00005993638,0.00001929178,0.00004904614,0.0006162896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01392664,"threshold_uncertainty_score":0.9816628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01043591337437482,"score_gpt":0.2298768355543121,"score_spread":0.2194409221799373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}