{"id":"W4230795123","doi":"10.3410/f.732632805.793550109","title":"Faculty Opinions recommendation of Citrullination of RGG motifs in FET proteins by PAD4 regulates protein aggregation and ALS susceptibility.","year":2018,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Citrullination; Chemistry; Computational biology; Cell biology; Biology; Genetics; Citrulline","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007886848,0.002174578,0.00143048,0.002148965,0.0006106179,0.001724714,0.001920376,0.002402763,0.0272279],"category_scores_gemma":[0.003823101,0.0004543077,0.001501247,0.002966134,0.0002922027,0.0008912813,0.001199233,0.001331417,0.02820165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001069557,"about_ca_system_score_gemma":0.001784573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01571978,"about_ca_topic_score_gemma":0.04139377,"domain_scores_codex":[0.9992552,0.0001027102,0.00007433457,0.0002727359,0.0001886646,0.0001062548],"domain_scores_gemma":[0.9988056,0.0003612383,0.000225577,0.0002011466,0.0002343955,0.0001719518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007211795,0.00009965545,0.01068894,0.002766711,0.0003158037,0.000125536,0.00004035486,0.0008843052,0.001377634,0.0005059686,0.9742478,0.008226132],"study_design_scores_gemma":[0.001008052,0.0001151784,0.04236859,0.0008775424,0.0004623216,0.0003609135,0.0001012485,0.002157109,0.002541625,0.001680613,0.948254,0.00007275564],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.001125185,0.0004876927,0.00008437699,0.0001276766,0.00003227818,0.000008941813,0.9970203,0.0003194629,0.0007939683],"genre_scores_gemma":[0.001622795,0.0001763101,0.0002555505,0.00008598709,0.000008199378,0.00002798253,0.9970732,0.0000336529,0.0007163288],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.0272279,"threshold_uncertainty_score":0.09108645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01398275265512229,"score_gpt":0.3216880170978866,"score_spread":0.3077052644427643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}