{"id":"W4231140912","doi":"10.3410/f.740031319.793585301","title":"Faculty Opinions recommendation of Genetic determinants of poor response to treatment in severe asthma.","year":2021,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Pharmacogenetics; Asthma; Genome-wide association study; Epigenetics; Medicine; Precision medicine; Disease; Bioinformatics; Genetic association; Genetic genealogy; Intensive care medicine; Single-nucleotide polymorphism; Immunology; Gene; Biology; Genetics; Internal medicine; Genotype; Population; Environmental health; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002119055,0.0009868395,0.001813118,0.003292884,0.0007242206,0.002602756,0.002388321,0.002283745,0.2354203],"category_scores_gemma":[0.03176969,0.0005303452,0.002306724,0.006503253,0.0002537499,0.001641952,0.001963391,0.0018478,0.09516577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001211557,"about_ca_system_score_gemma":0.004672049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01892257,"about_ca_topic_score_gemma":0.04740764,"domain_scores_codex":[0.9977036,0.0005100212,0.0005740459,0.0005548868,0.0004355899,0.0002218172],"domain_scores_gemma":[0.9855526,0.00509313,0.002524267,0.001648766,0.004001065,0.001180277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000109324,0.00001110163,0.003042282,0.002680121,0.0001672544,0.00001991,0.00001716795,0.00007250585,0.00005673784,0.0002988724,0.9886627,0.004862035],"study_design_scores_gemma":[0.0009625198,0.00002608282,0.02300205,0.002750962,0.0003483967,0.0001353271,0.00006703451,0.0002683371,0.0001851961,0.001289229,0.9709142,0.00005059876],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"review","genre_scores_codex":[0.00008902048,0.0001413572,0.00005224453,0.0003848519,0.00005598737,0.00002706167,0.9980953,0.0000928154,0.00106135],"genre_scores_gemma":[0.001260506,0.0003931077,0.0006776407,0.0007505275,0.00008678352,0.0003364022,0.9939975,0.0001191648,0.002378379],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.2354203,"threshold_uncertainty_score":0.7875595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02989102726084959,"score_gpt":0.3689095762014797,"score_spread":0.3390185489406302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}