{"id":"W4231448523","doi":"10.21203/rs.2.469/v1","title":"Genetic basis for prediction of responsiveness to dietary plant sterol intervention (GenePredict-PS): a study protocol for a double-blind, placebo-controlled, randomized two-period crossover study","year":2019,"lang":"en","type":"preprint","venue":"Research Square","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Crossover study; Double blind; Placebo; Protocol (science); Crossover; Period (music); Randomized controlled trial; Medicine; Internal medicine; Computer science; Artificial intelligence; Physics; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006482226,0.003942033,0.004923359,0.001358214,0.001739408,0.001160207,0.001898157,0.004062359,0.01886918],"category_scores_gemma":[0.005169499,0.001972774,0.001842391,0.0009786666,0.003356695,0.001198993,0.001178488,0.003576465,0.003284388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001170809,"about_ca_system_score_gemma":0.003009571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001051364,"about_ca_topic_score_gemma":0.000915363,"domain_scores_codex":[0.9953659,0.002135456,0.0003507478,0.001000699,0.000457234,0.0006901131],"domain_scores_gemma":[0.9968041,0.001186463,0.0005359249,0.0006030928,0.0002426746,0.0006278055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9568359,0.02830991,0.0007722477,0.0003243955,0.0002768276,0.00005672644,0.00007941098,0.0008067064,0.005115878,0.0004054015,0.0005965437,0.006420136],"study_design_scores_gemma":[0.8023599,0.1860834,0.003922713,0.0000543356,0.0005453274,0.00002736601,0.00002660851,0.001219458,0.002551134,0.0007382058,0.002410247,0.00006133582],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.6536124,0.0008245734,0.01295399,0.0008492201,0.000870781,0.3206504,0.005852074,0.0006419744,0.003744668],"genre_scores_gemma":[0.4297349,0.000801207,0.02053123,0.001030053,0.000679619,0.5360193,0.002115608,0.0001879615,0.00890006],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.01886918,"threshold_uncertainty_score":0.06312376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1255406996876806,"score_gpt":0.4609442575677938,"score_spread":0.3354035578801132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}