{"id":"W4231453870","doi":"10.14341/probl201864162-66","title":"Leptin resistance: unsolved diagnostic issues","year":2018,"lang":"en","type":"article","venue":"Problems of Endocrinology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill-Queen's University Press","funders":"","keywords":"Leptin; Leptin receptor; Internal medicine; Endocrinology; Receptor; Insulin resistance; Energy homeostasis; Homeostasis; Biology; Obesity; Dyslipidemia; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007179934,0.0001152623,0.0002038377,0.0001016779,0.0001135549,0.00001282918,0.0003091501,0.00005257417,0.0004222014],"category_scores_gemma":[0.001069096,0.0001069932,0.00004930614,0.0001968544,0.0006127267,0.0001090475,0.0001063535,0.00009362236,0.0003393971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001220351,"about_ca_system_score_gemma":0.00002232661,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003770151,"about_ca_topic_score_gemma":0.0001049131,"domain_scores_codex":[0.9987583,0.00009208523,0.0002846766,0.0003430448,0.0001612354,0.0003607032],"domain_scores_gemma":[0.998949,0.0004369802,0.0001423946,0.0003322048,0.00009235741,0.00004704533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008471356,0.0002163045,0.01350822,0.0001242725,0.00001192282,0.00002484033,0.0005689605,0.0000223605,0.8452269,0.1288723,0.008191803,0.003147441],"study_design_scores_gemma":[0.0003674353,0.0001900883,0.01306115,0.00004398201,0.000006447478,0.000009700367,0.00001430562,0.00002211715,0.8341554,0.01568041,0.1363287,0.0001202642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9544243,0.0004382934,0.0002384123,0.002755081,0.0003516546,0.0002864835,0.0000082,0.0001314902,0.04136607],"genre_scores_gemma":[0.9939743,0.0004823905,0.0008110327,0.0002366279,0.000156422,0.00001743136,0.000001472852,0.00001239628,0.004307935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1281369,"threshold_uncertainty_score":0.4622809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03356382236304672,"score_gpt":0.2921920620218538,"score_spread":0.258628239658807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}