{"id":"W4231494923","doi":"10.1162/15353500200404157","title":"Combined in Vivo Bioluminescence and Fluorescence Imaging for Cancer Gene Therapy","year":2004,"lang":"en","type":"article","venue":"Molecular Imaging","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Bioluminescence imaging; Luciferase; Bioluminescence; In vivo; Genetic enhancement; Colocalization; Fluorescence-lifetime imaging microscopy; Cancer research; Viral vector; Adenoviridae; Preclinical imaging; Pathology; Medicine; Biology; Molecular biology; Recombinant DNA; Gene; Fluorescence; Transfection","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002508361,0.0002097964,0.0001614503,0.000106349,0.000092938,0.00006148889,0.0002533074,0.00004478206,0.000009374821],"category_scores_gemma":[0.00004182328,0.0002187248,0.00006872992,0.000170139,0.0001586878,0.0000101898,0.00009801679,0.00009648033,0.000001152997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004697476,"about_ca_system_score_gemma":0.0001442489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001843503,"about_ca_topic_score_gemma":0.00008967116,"domain_scores_codex":[0.9985878,0.00004905941,0.0001918865,0.0005405589,0.0001537749,0.0004768745],"domain_scores_gemma":[0.9993988,0.000008896255,0.00004947707,0.0003452533,0.0001021523,0.0000954255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005624976,0.0000504505,0.0112972,0.00001408714,0.0000174655,0.00002747243,0.00005279335,0.000170485,0.9730089,0.00002094302,0.0000665123,0.01471123],"study_design_scores_gemma":[0.002902814,0.00022788,0.0008773138,0.00003908113,0.000004380198,0.00001146841,0.00002952716,0.00075266,0.9936042,0.0002634762,0.001018189,0.0002690556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9831985,0.008536441,0.005744704,0.001815475,0.00007564365,0.0005444839,0.00002138196,0.00001989328,0.00004349136],"genre_scores_gemma":[0.9949943,0.001079406,0.002243587,0.001327267,0.00006979792,0.0001758976,0.00002507816,0.00005423329,0.00003039683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0205953,"threshold_uncertainty_score":0.8919339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01090773034934486,"score_gpt":0.2948463326730406,"score_spread":0.2839386023236958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}