{"id":"W4231494923","doi":"10.1162/15353500200404157","title":"Combined in Vivo Bioluminescence and Fluorescence Imaging for Cancer Gene Therapy","year":2004,"lang":"en","type":"article","venue":"Molecular Imaging","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Bioluminescence imaging; Luciferase; Bioluminescence; In vivo; Genetic enhancement; Colocalization; Fluorescence-lifetime imaging microscopy; Cancer research; Viral vector; Adenoviridae; Preclinical imaging; Pathology; Medicine; Biology; Molecular biology; Recombinant DNA; Gene; Fluorescence; Transfection","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007414257,0.0009470676,0.0005734201,0.0006831631,0.000213117,0.0006569204,0.0005189372,0.000744301,0.001993886],"category_scores_gemma":[0.0002583025,0.000518117,0.0003779288,0.000340002,0.0004851611,0.0007402492,0.0006185931,0.0009586447,0.0006818618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006392054,"about_ca_system_score_gemma":0.0004222669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007197552,"about_ca_topic_score_gemma":0.001250078,"domain_scores_codex":[0.9994306,0.0001790927,0.00001860418,0.0001176689,0.0001893434,0.00006476618],"domain_scores_gemma":[0.9999157,0.00002567893,0.00001750476,0.00001121578,0.00001411318,0.00001580706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008310729,0.00004462405,0.00007449355,0.00006986046,0.000008322471,0.000027116,0.00001294595,0.0001704813,0.9940147,0.0003161404,0.0001033998,0.005074821],"study_design_scores_gemma":[0.00004677353,0.0004218795,0.0009185324,0.00001619768,0.00003102041,0.000580558,0.00001324023,0.005605465,0.9848831,0.0002526665,0.007213575,0.00001703208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.4499582,0.03277998,0.497846,0.001435208,0.0003784432,0.0005007286,0.0005327106,0.00120025,0.01536856],"genre_scores_gemma":[0.6704795,0.01293591,0.2971271,0.0003607204,0.0001728451,0.0007061195,0.0004877627,0.0002196833,0.01751034],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001993886,"threshold_uncertainty_score":0.006670237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01090773034934486,"score_gpt":0.2948463326730406,"score_spread":0.2839386023236958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}