{"id":"W4231561986","doi":"10.1016/j.jaad.2021.06.697","title":"28032 Rapid itch improvement with upadacitinib with or without concomitant topical corticosteroids (TCS) in moderate-to-severe atopic dermatitis (AD): Results from 3 phase 3 studies (Measure Up 1, Measure Up 2, and AD Up)","year":2021,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Probity Medical Research; University of British Columbia","funders":"","keywords":"Medicine; Placebo; Concomitant; Atopic dermatitis; Randomized controlled trial; Anesthesia; Gastroenterology; Internal medicine; Dermatology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008419854,0.0007121399,0.001757842,0.0003992902,0.0002948267,0.0007548447,0.0004806407,0.0007711554,0.006703432],"category_scores_gemma":[0.0005301423,0.0002523544,0.001553089,0.0003050428,0.0003636818,0.0006566243,0.0002603909,0.002379988,0.001154743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000344214,"about_ca_system_score_gemma":0.0004029957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007307324,"about_ca_topic_score_gemma":0.002694116,"domain_scores_codex":[0.9997898,0.0000660275,0.00001469884,0.00003251201,0.00003538386,0.00006164156],"domain_scores_gemma":[0.9997599,0.00006345593,0.00004257525,0.00002181681,0.00003245314,0.00007989523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3147502,0.02811048,0.004990032,0.006343745,0.004493207,0.0005133324,0.0002735487,0.001816627,0.0543925,0.0005158212,0.01926266,0.5645379],"study_design_scores_gemma":[0.6001045,0.326589,0.0372254,0.0007765435,0.003341194,0.001488006,0.0002215797,0.002469321,0.01145113,0.0004469268,0.01577132,0.0001151034],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9506508,0.03584956,0.0008825588,0.0009574938,0.0005306142,0.001604344,0.001532561,0.0004852895,0.007506862],"genre_scores_gemma":[0.9806296,0.01059818,0.001268277,0.001295508,0.0001992953,0.0007394006,0.001849874,0.00003490605,0.003384798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006703432,"threshold_uncertainty_score":0.02242523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03587329796587969,"score_gpt":0.3306006196279506,"score_spread":0.2947273216620709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}