{"id":"W4231586227","doi":"10.1016/j.nmd.2020.08.284","title":"DMD – THERAPY","year":2020,"lang":"en","type":"article","venue":"Neuromuscular Disorders","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Dystrophin; Myogenesis; Duchenne muscular dystrophy; CRISPR; Biology; HEK 293 cells; Utrophin; Reprogramming; Cell biology; Muscular dystrophy; mdx mouse; Genome editing; Bioinformatics; Computational biology; Genetics; Gene; Myocyte","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005364213,0.0006658854,0.0005257479,0.0006482697,0.0007157694,0.0008506593,0.0005354752,0.001334027,0.09548803],"category_scores_gemma":[0.000519316,0.0001427979,0.0004929852,0.0002602465,0.0005931474,0.0004601293,0.001238052,0.001333823,0.03784269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004886728,"about_ca_system_score_gemma":0.0007383811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004618239,"about_ca_topic_score_gemma":0.0009391271,"domain_scores_codex":[0.9995453,0.00008186058,0.00003025052,0.00008863361,0.0002053522,0.00004859784],"domain_scores_gemma":[0.9998285,0.00003501409,0.00002309704,0.00003004128,0.0000357083,0.00004756724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005491772,0.0003219998,0.001034027,0.001060479,0.00008050391,0.002026619,0.0001808651,0.000892374,0.07821179,0.04091287,0.2157351,0.6589943],"study_design_scores_gemma":[0.00006889868,0.000238418,0.001344519,0.0002584584,0.00003149247,0.003644891,0.00003112368,0.0002694142,0.01289894,0.004513835,0.9766849,0.00001522952],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.02908304,0.03030636,0.06359251,0.02214268,0.005919685,0.0008811674,0.005594654,0.004475185,0.8380049],"genre_scores_gemma":[0.1430924,0.01729948,0.02670388,0.01597956,0.002104558,0.0009266963,0.004041287,0.0008073825,0.7890449],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.09548803,"threshold_uncertainty_score":0.3194393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008884208831898223,"score_gpt":0.2628504436723857,"score_spread":0.2539662348404875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}