{"id":"W4231617406","doi":"10.1089/104303403322542266","title":"A Coumermycin/Novobiocin-Regulated Gene Expression System","year":2003,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Biotechnology Research Institute","funders":"","keywords":"Transactivation; TetR; DNA gyrase; Novobiocin; Biology; Repressor; Molecular biology; Gene; Gene expression; Regulation of gene expression; Genetics; Cell biology; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005681794,0.0003606767,0.0002934673,0.0001106229,0.0003618399,0.00005568632,0.0004348657,0.0002687596,0.0003809622],"category_scores_gemma":[0.00001214458,0.0003265849,0.0001820204,0.0001918405,0.000125353,0.000005602603,0.0000589826,0.0001586815,0.00008899355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006467605,"about_ca_system_score_gemma":0.000137571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001029791,"about_ca_topic_score_gemma":0.00001846298,"domain_scores_codex":[0.997557,0.000421794,0.000357565,0.0006914313,0.0003681617,0.00060407],"domain_scores_gemma":[0.9983916,0.000009519194,0.000127005,0.001100484,0.0001707751,0.0002005971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008913517,0.0001239437,0.0001814601,0.00001373634,0.000114556,0.00001527807,0.00008627662,0.00008206775,0.9955574,0.00008412121,0.001929372,0.0009204147],"study_design_scores_gemma":[0.002395502,0.001991508,0.0002205246,0.00001835945,0.000007540643,0.0000581486,0.00006868914,0.00001230436,0.9815384,0.00005364464,0.01325197,0.000383482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899275,0.007188294,0.0003389392,0.00002257591,0.000160425,0.0005476421,0.0000198505,0.00008975036,0.001704981],"genre_scores_gemma":[0.9956705,0.0005705734,0.0005191179,0.0002592851,0.0003197,0.00009490622,0.0002284795,0.0001150887,0.00222234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01401909,"threshold_uncertainty_score":0.9999186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02706585796595672,"score_gpt":0.2990417683000122,"score_spread":0.2719759103340555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}