{"id":"W4231652458","doi":"10.1016/j.neurobiolaging.2011.12.005","title":"Selective inhibition of the membrane attack complex of complement by low molecular weight components of the aurin tricarboxylic acid synthetic complex","year":2012,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Division of Ocean Sciences; Fondation pour la Recherche sur Alzheimer","keywords":"Complement membrane attack complex; Lysis; Complement system; Anaphylatoxin; Bystander effect; Biochemistry; Chemistry; Hemolysis; Innate immune system; Biology; Cell biology; Immune system; Immunology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003243427,0.0002674469,0.0007506955,0.0001276532,0.0001353189,0.000001782898,0.0006185499,0.0001131496,0.0004245657],"category_scores_gemma":[0.00005989316,0.0001857695,0.0003167357,0.0003261818,0.00105484,0.00004504237,0.0004756803,0.0002195605,0.000007848866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004357577,"about_ca_system_score_gemma":0.00003697341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001173956,"about_ca_topic_score_gemma":0.000007117395,"domain_scores_codex":[0.9967076,0.001460666,0.0009772934,0.000294275,0.0001130186,0.0004471861],"domain_scores_gemma":[0.9976542,0.0003527027,0.001136515,0.0006610043,0.0001685644,0.00002702193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008328461,0.0005418099,0.03887357,0.0002355908,0.0002743685,1.637083e-7,0.0002662399,0.00004464444,0.9575134,0.000441052,0.001688548,0.00003731638],"study_design_scores_gemma":[0.001188643,0.0001194613,0.2205825,0.0001688692,0.0001317071,0.00001346593,0.00007841454,0.00001361737,0.777142,0.00002794435,0.0004195183,0.0001138325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968091,0.0006293507,0.00004045355,0.0004265397,0.0004234908,0.0008341487,0.0005338352,0.0000187672,0.0002842889],"genre_scores_gemma":[0.9995829,0.00001005414,0.00003243237,0.000142208,0.00001174513,0.00002136542,0.0001587242,0.00002145341,0.00001914722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1817089,"threshold_uncertainty_score":0.7575461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02524491438124064,"score_gpt":0.254793492591665,"score_spread":0.2295485782104244,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}