{"id":"W4231985646","doi":"10.1159/000440842","title":"Tau Immunotherapy","year":2015,"lang":"en","type":"review","venue":"Neurodegenerative Diseases","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; National Institutes of Health; National Institute of Neurological Disorders and Stroke; H. Lundbeck A/S; York University","keywords":"Epitope; Tau pathology; Tau protein; Immunotherapy; Antibody; Medicine; Disease; Neuroscience; Clinical trial; Immunology; Pathology; Alzheimer's disease; Psychology; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006867891,0.0007574906,0.002196527,0.0002759075,0.0001483315,0.00008064907,0.0002369282,0.0001804885,0.0004434171],"category_scores_gemma":[0.00009603086,0.0005195629,0.001105454,0.0004288982,0.0001866145,0.0001114958,0.0000993014,0.0003728183,0.0009884114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002429016,"about_ca_system_score_gemma":0.002775654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009609902,"about_ca_topic_score_gemma":8.150379e-7,"domain_scores_codex":[0.9968644,0.000461081,0.0004841396,0.0008316431,0.0008022111,0.0005564812],"domain_scores_gemma":[0.9973401,0.0001099679,0.0002031034,0.0008813333,0.0003389088,0.00112652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001877273,0.001524045,0.00012345,0.004623725,0.01406467,0.001634429,0.00002156125,3.591947e-7,6.143484e-7,0.000115948,0.03104062,0.9466628],"study_design_scores_gemma":[0.001236883,0.000531689,0.00007573873,0.002186157,0.006424977,0.00009462752,0.000007256112,0.000002923053,0.0000064168,0.00004358243,0.9889809,0.0004088277],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003672135,0.9947697,0.000003325987,0.00003877817,0.0002064484,0.001979752,0.001565648,0.0001531399,0.001246465],"genre_scores_gemma":[0.00006053326,0.9945682,0.00004932995,0.0002012187,0.0006047463,0.000705377,0.002915043,0.0001790941,0.0007164206],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9579403,"threshold_uncertainty_score":0.9997894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1019276784436676,"score_gpt":0.4112627709815896,"score_spread":0.309335092537922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}