{"id":"W4232133412","doi":"10.1067/mjd.2000.110042","title":"Reply","year":2000,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Glutathione Transferases and Polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CYP2D6; Pharmacology; Pharmacogenetics; Medicine; Fluconazole; Population; Terbinafine; Drug metabolism; Drug; Itraconazole; Cytochrome P450; Genetics; Biology; Internal medicine; Metabolism; Dermatology; Antifungal; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007737923,0.00008547727,0.0002659499,0.00003512759,0.00003503086,0.000002742337,0.0003830153,0.00005336088,0.00006206107],"category_scores_gemma":[0.00002253637,0.00005679949,0.0002255281,0.0001076084,0.0003497976,0.000003263248,0.00002443026,0.0001936936,0.000005574165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003832608,"about_ca_system_score_gemma":0.00004191428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001045839,"about_ca_topic_score_gemma":4.465406e-7,"domain_scores_codex":[0.9991477,0.0001239163,0.0003822242,0.0000852063,0.0001150822,0.0001458521],"domain_scores_gemma":[0.9994069,0.00001891856,0.0003739796,0.0001195449,0.00002475314,0.00005584299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001358925,0.0001721854,0.02528013,0.00002600448,0.0003946928,0.00003415505,0.0001528099,0.0003035922,0.8818267,0.0003395533,0.05301765,0.03709362],"study_design_scores_gemma":[0.0009952424,0.0004369437,0.0352682,0.00003030684,0.0001059079,0.012601,0.00007003302,0.00001524304,0.4532931,0.0004885406,0.4965084,0.0001870323],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810131,0.0009053281,0.00006117476,0.01752973,0.00005848394,0.00003595162,0.000005429964,0.000001630868,0.0003891379],"genre_scores_gemma":[0.9922735,0.0009565364,0.0003567817,0.006080323,0.0001043096,5.885976e-7,5.218338e-7,0.000009530409,0.0002179075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4434907,"threshold_uncertainty_score":0.2316216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007713922858211596,"score_gpt":0.2641639529015511,"score_spread":0.2564500300433395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}