{"id":"W4232144512","doi":"10.7150/thno.17736","title":"Theranostic DNAzymes","year":2017,"lang":"en","type":"review","venue":"Theranostics","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":248,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"China Scholarship Council; Central South University; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Deoxyribozyme; Cleave; Computational biology; DNA; RNA; Nanotechnology; Nucleic acid; Biology; Chemistry; Gene; Genetics; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003345231,0.001002824,0.0008268672,0.00157908,0.0002803844,0.000846,0.0007102533,0.001259233,0.003667745],"category_scores_gemma":[0.000401298,0.0003379024,0.0005233814,0.001185921,0.0003624099,0.0009477338,0.0006703489,0.001708834,0.003082528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006455231,"about_ca_system_score_gemma":0.0004720119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004187819,"about_ca_topic_score_gemma":0.0006522202,"domain_scores_codex":[0.9997538,0.00002761344,0.00001798765,0.00006228282,0.0001041645,0.00003411496],"domain_scores_gemma":[0.9998984,0.00003579187,0.00002016363,0.00000508155,0.00002942568,0.00001115454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007322955,0.0001330998,0.000205979,0.01549172,0.00008499899,0.0004995896,0.0001485371,0.001047207,0.09886981,0.01836824,0.03742275,0.8276548],"study_design_scores_gemma":[0.00001053407,0.00007304106,0.0001849126,0.0006313688,0.00002795439,0.000959155,0.00002434996,0.0002247629,0.02128587,0.001402164,0.9751557,0.00002020901],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001923508,0.9750379,0.005588685,0.0005828903,0.0009612124,0.00006240782,0.000140435,0.0001136872,0.01558926],"genre_scores_gemma":[0.01422835,0.9596881,0.005485107,0.0009520085,0.0003405451,0.0001253778,0.0003118753,0.00002485734,0.0188437],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003667745,"threshold_uncertainty_score":0.01226979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08085513549860088,"score_gpt":0.4024890990040754,"score_spread":0.3216339635054746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}