{"id":"W4232241812","doi":"10.3410/f.740056078.793585815","title":"Faculty Opinions recommendation of Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity.","year":2021,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Immunogenicity; Epigenetics; Gene silencing; Computational biology; Cancer research; Chemistry; Biology; Genetics; Gene; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001790378,0.001840658,0.001731238,0.00200318,0.0008352964,0.002776994,0.002807008,0.002892802,0.06804892],"category_scores_gemma":[0.009971333,0.0005691761,0.001839772,0.003198087,0.0003320552,0.001139901,0.001634345,0.001710649,0.06610084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001493945,"about_ca_system_score_gemma":0.003037866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02183667,"about_ca_topic_score_gemma":0.06151856,"domain_scores_codex":[0.9985781,0.000288406,0.0001287828,0.0004263871,0.0003832674,0.0001950446],"domain_scores_gemma":[0.9971584,0.0009508288,0.0003373912,0.0005851259,0.0006082101,0.0003600118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002274225,0.00003682222,0.002437372,0.001008957,0.0001198886,0.00002586047,0.00001400792,0.0003197634,0.0002985894,0.0002642723,0.9907227,0.004524231],"study_design_scores_gemma":[0.0009679963,0.00008603467,0.0141807,0.0007008398,0.0003163444,0.0001731478,0.00007248805,0.001570527,0.001616167,0.002214632,0.9780418,0.00005936186],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0004148404,0.0002345976,0.00008582039,0.0002179643,0.00004992929,0.00001344327,0.9976565,0.0002879626,0.001038852],"genre_scores_gemma":[0.001200282,0.0001330596,0.0003547731,0.0001621332,0.00001519347,0.00005149074,0.9966191,0.00005107231,0.001412888],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.06804892,"threshold_uncertainty_score":0.2276464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01850013192067397,"score_gpt":0.3256517683158498,"score_spread":0.3071516363951758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}