{"id":"W4232378745","doi":"10.21203/rs.3.rs-30627/v3","title":"HLA-B*35 as a new marker for susceptibility to Human T-cell Lymphotropic Virus type 1 (HTLV-1) Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) in patients living in Argentina","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Kimberly-Clark (Canada)","funders":"National Institute of Mental Health; Fondo para la Investigación Científica y Tecnológica; University of California, San Francisco; National Institutes of Health; Consejo Nacional de Investigaciones Científicas y Técnicas; Starr Foundation","keywords":"Tropical spastic paraparesis; Myelopathy; Virology; Human leukocyte antigen; Medicine; Human T-lymphotropic virus; Immunology; Spinal cord; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001035591,0.0005895243,0.001194497,0.0007524538,0.0004386479,0.0000866124,0.0008664103,0.00108955,0.0007347144],"category_scores_gemma":[0.006753008,0.0005574341,0.0003284003,0.0009076336,0.0002666573,0.00005476981,0.002542969,0.002114249,0.0008101366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001262076,"about_ca_system_score_gemma":0.0009593161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005431393,"about_ca_topic_score_gemma":0.00809072,"domain_scores_codex":[0.9936333,0.001740506,0.0009710514,0.001570684,0.0003602937,0.001724116],"domain_scores_gemma":[0.9971398,0.001095523,0.000218639,0.0007507754,0.0005425602,0.0002527614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001532417,0.001657199,0.9574372,0.0008125984,0.0002235233,0.00003464212,0.002248994,0.00003646522,0.02126737,0.00004623547,0.01368294,0.001020428],"study_design_scores_gemma":[0.002884297,0.001844834,0.9860038,0.001136844,0.00004546059,6.232288e-7,0.0005113229,0.00001649016,0.001937486,0.0007114327,0.004299566,0.0006078061],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928773,0.002071382,0.00002246737,0.0004050568,0.00076001,0.002946547,0.0002549794,0.00009506297,0.0005672111],"genre_scores_gemma":[0.9942676,0.0003257594,0.00006001543,0.0001047333,0.0001248859,0.0003526513,0.000507389,0.00007918911,0.004177719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02856665,"threshold_uncertainty_score":0.9999679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05145761571575894,"score_gpt":0.3430857626212453,"score_spread":0.2916281469054864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}