{"id":"W4232379576","doi":"10.1016/j.bmc.2006.11.020","title":"Investigating biological activity spectrum for novel quinoline analogues","year":2006,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Korle-Bu Neuroscience Foundation; Vedecká Grantová Agentúra MŠVVaŠ SR a SAV; Ministerstvo Školství, Mládeže a Tělovýchovy","keywords":"Chemistry; Lipophilicity; Spinacia; Quinoline; Biological activity; Chlorella vulgaris; Photosynthesis; Spinach; Stereochemistry; Chloroplast; Organic chemistry; Biochemistry; Botany; Algae; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001888682,0.000148979,0.0001726389,0.0002724698,0.0001142618,0.000149162,0.0002497563,0.0002093285,0.002268724],"category_scores_gemma":[0.0002555316,0.00008316563,0.0001605547,0.0002015232,0.0001364536,0.0002504813,0.00009909885,0.0003095761,0.0002459445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001506679,"about_ca_system_score_gemma":0.0000987115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005599999,"about_ca_topic_score_gemma":0.0004928986,"domain_scores_codex":[0.9999175,0.00002126315,0.000004389084,0.00001754591,0.00001612729,0.00002318678],"domain_scores_gemma":[0.9998479,0.0000710778,0.00001660008,0.00001560216,0.00003264271,0.00001614872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005450508,0.00005682076,0.0003622457,0.0000668487,0.000006041964,0.0001132867,0.00003527425,0.000483575,0.993905,0.0001783074,0.0000561068,0.004191381],"study_design_scores_gemma":[0.00005299631,0.002495842,0.002820849,0.000008487006,0.00003136259,0.0002868366,0.00004874312,0.001390298,0.9908517,0.0001252653,0.001878005,0.000009569664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920667,0.002799058,0.001919508,0.00006890303,0.000008652236,0.00003102361,0.0002625023,0.00003104009,0.002812691],"genre_scores_gemma":[0.9968057,0.0009531638,0.000819303,0.00002512093,0.000005890147,0.00001259252,0.0003000983,0.00000721976,0.00107105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002268724,"threshold_uncertainty_score":0.007589638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02309802873300679,"score_gpt":0.2400569060162904,"score_spread":0.2169588772832836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}