{"id":"W4232408201","doi":"10.1016/j.atherosclerosissup.2018.04.476","title":"Treatment with Volanesorsen (VLN) Reduced Triglycerides and Pancreatitis in Patients with FCS and sHTG vs Placebo: Results of the APPROACH and COMPASS Studies","year":2018,"lang":"en","type":"article","venue":"Atherosclerosis Supplements","topic":"Pancreatitis Pathology and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Université du Québec à Chicoutimi","funders":"","keywords":"Medicine; Triglyceride; Hypertriglyceridemia; Internal medicine; Acute pancreatitis; Gastroenterology; Diabetes mellitus; Alcohol consumption; Pancreatitis; High-density lipoprotein; Cholesterol; Endocrinology; Alcohol; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001061662,0.0008318393,0.002000922,0.0004445255,0.0003070763,0.0006468333,0.0004031023,0.0008406354,0.003885235],"category_scores_gemma":[0.0009606099,0.0003799856,0.001716964,0.0004109768,0.0007451635,0.00066646,0.0003435608,0.001250315,0.0003037972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003871955,"about_ca_system_score_gemma":0.0007668023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001490055,"about_ca_topic_score_gemma":0.00273565,"domain_scores_codex":[0.9995911,0.0002141209,0.00004782305,0.00004313322,0.00004112132,0.00006278959],"domain_scores_gemma":[0.9994256,0.000167863,0.0001317865,0.00005606953,0.00004007873,0.000178646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9437158,0.006255299,0.003712648,0.0004555625,0.002510579,0.00006084596,0.00009703658,0.0001338101,0.01113548,0.00007754743,0.000222237,0.03162323],"study_design_scores_gemma":[0.4527837,0.4706205,0.05571337,0.0001833665,0.008001169,0.0001923675,0.0003529473,0.0005263888,0.009263453,0.000201192,0.002102819,0.0000585948],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952885,0.003381665,0.0001316473,0.0002133426,0.00006477717,0.00009754096,0.0001583051,0.0000230069,0.0006412214],"genre_scores_gemma":[0.9947395,0.002947678,0.0004144433,0.0001828547,0.0001547109,0.00007854041,0.0002841429,0.000007724437,0.001190493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003885235,"threshold_uncertainty_score":0.01299745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02382003051515174,"score_gpt":0.261942161939602,"score_spread":0.2381221314244502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}