{"id":"W4232423268","doi":"10.3410/f.1004518.35510","title":"Faculty Opinions recommendation of A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants.","year":2002,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Genetics, Bioinformatics, and Biomedical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"","keywords":"Mutant; Chaperone (clinical); Peptide; Core (optical fiber); Domain (mathematical analysis); Cell biology; Chemistry; Computational biology; Biology; Computer science; Gene; Biochemistry; Medicine; Telecommunications","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001271024,0.00296154,0.001484231,0.002860219,0.0007772679,0.002087957,0.002983928,0.002737821,0.02363142],"category_scores_gemma":[0.005339732,0.0007508371,0.001596064,0.004269209,0.0002784708,0.0009809312,0.0009602834,0.001676736,0.03119397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001241888,"about_ca_system_score_gemma":0.002367165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02509993,"about_ca_topic_score_gemma":0.05580711,"domain_scores_codex":[0.9990602,0.0001358311,0.0000977806,0.0002960908,0.00028886,0.0001212928],"domain_scores_gemma":[0.9976254,0.0006174646,0.0002804245,0.0006379046,0.0005136309,0.000325185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00056981,0.0001662773,0.003779156,0.001212092,0.0001857701,0.00008829321,0.00002279793,0.001005941,0.001201331,0.0002817461,0.9839156,0.0075712],"study_design_scores_gemma":[0.001862212,0.0002008412,0.02965432,0.0003564705,0.0004229249,0.0003185492,0.0001152869,0.009327814,0.01108634,0.001653694,0.9448918,0.0001097966],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.00120784,0.000124455,0.0001648911,0.0001306545,0.00003366767,0.00002306501,0.9966856,0.0009614651,0.000668383],"genre_scores_gemma":[0.001136218,0.00005385866,0.0004606446,0.00003839811,0.000004391573,0.00003433365,0.9975255,0.00006571488,0.0006809194],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.02509993,"threshold_uncertainty_score":0.07905501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06986313359504066,"score_gpt":0.3707635033463408,"score_spread":0.3009003697513002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}