{"id":"W4232479412","doi":"10.1139/o01-116","title":"The emerging role of class II histone deacetylases","year":2001,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":150,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Boehringer Ingelheim Stiftung; Fonds De La Recherche Scientifique - FNRS; Centre International de Recherche sur le Cancer; Gladstone Institutes","keywords":"HDAC4; Corepressor; Histone; Biology; HDAC11; Histone Acetyltransferases; Histone methyltransferase; Histone deacetylase 5; Histone code; Histone deacetylase; Chromatin; Histone deacetylase 2; Acetylation; Genetics; Transcriptional regulation; Histone H2A; SAP30; Cell biology; Repressor; Transcription factor; Gene; Nucleosome","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002611271,0.0003860603,0.00039808,0.0002394795,0.0002144489,0.001011815,0.0002756952,0.0004667891,0.00156017],"category_scores_gemma":[0.0001579154,0.00009926559,0.0002020863,0.0002837749,0.0004810925,0.0007436805,0.0003226066,0.0009450093,0.0007276817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004632194,"about_ca_system_score_gemma":0.0004276775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004088111,"about_ca_topic_score_gemma":0.0005874408,"domain_scores_codex":[0.9998882,0.00001069232,0.0000075059,0.00003574934,0.00003137107,0.00002652506],"domain_scores_gemma":[0.9999019,0.00001552639,0.0000186674,0.000009728025,0.0000264169,0.00002764262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004062549,0.0000624731,0.004405091,0.001781875,0.00007399792,0.0007566966,0.0002209252,0.0004869195,0.5205551,0.04340823,0.007916712,0.4199257],"study_design_scores_gemma":[0.00003397331,0.0003917028,0.01532268,0.00013533,0.00009009302,0.003393581,0.000232555,0.0008347385,0.1092419,0.01777021,0.8525186,0.00003470451],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05806705,0.8933499,0.01893357,0.005970303,0.001850551,0.00002222697,0.0002452841,0.0002837479,0.02127731],"genre_scores_gemma":[0.3134671,0.6508104,0.01180154,0.002870503,0.002436641,0.00003863561,0.000527491,0.00003725656,0.01801041],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00156017,"threshold_uncertainty_score":0.00521934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00620145437478505,"score_gpt":0.2621294169623262,"score_spread":0.2559279625875412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}