{"id":"W4232479412","doi":"10.1139/o01-116","title":"The emerging role of class II histone deacetylases","year":2001,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":150,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Boehringer Ingelheim Stiftung; Fonds De La Recherche Scientifique - FNRS; Centre International de Recherche sur le Cancer; Gladstone Institutes","keywords":"HDAC4; Corepressor; Histone; Biology; HDAC11; Histone Acetyltransferases; Histone methyltransferase; Histone deacetylase 5; Histone code; Histone deacetylase; Chromatin; Histone deacetylase 2; Acetylation; Genetics; Transcriptional regulation; Histone H2A; SAP30; Cell biology; Repressor; Transcription factor; Gene; Nucleosome","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002311231,0.0001703242,0.0001613065,0.00002449118,0.0003473092,0.000009149047,0.0002637126,0.0002624842,0.00002759268],"category_scores_gemma":[0.0001126952,0.0001350658,0.00008580263,0.00009804186,0.0005596189,0.000002121015,0.0002756988,0.0001405169,0.000004796304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001894269,"about_ca_system_score_gemma":0.00009056092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003453625,"about_ca_topic_score_gemma":0.00001384867,"domain_scores_codex":[0.9988435,0.00006552461,0.0002589997,0.0003815423,0.00009100377,0.0003594614],"domain_scores_gemma":[0.9992311,0.00004040146,0.0001108706,0.0004180773,0.00009261394,0.0001069559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001273733,0.00006261439,0.0005508004,0.0000198899,0.00002279194,0.000001875278,0.00003005747,0.00000196243,0.9904272,0.00007104934,0.001492028,0.007192349],"study_design_scores_gemma":[0.0002259645,0.0001549414,0.00002498045,0.000004379117,0.000006437953,0.00002146091,0.000159338,0.00001791457,0.6613264,0.0000356276,0.337918,0.0001045544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9686399,0.01867908,0.00002001868,0.0002283753,0.00007863465,0.00008893879,0.0000193197,0.00001089215,0.01223481],"genre_scores_gemma":[0.9900877,0.002987083,0.00006634567,0.0000444679,0.0002249939,0.00002146762,0.00009438247,0.00001597484,0.00645761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.336426,"threshold_uncertainty_score":0.5507822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00620145437478505,"score_gpt":0.2621294169623262,"score_spread":0.2559279625875412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}