{"id":"W4232550090","doi":"10.1002/(sici)1526-968x(200002)26:2<99::aid-gene1>3.3.co;2-2","title":"Cre recombinase: The universal reagent for genome tailoring","year":2000,"lang":"en","type":"article","venue":"genesis","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Recombinase; Genome; Biology; Cre recombinase; Computational biology; Genetics; Gene; Recombination; Transgene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001754754,0.00125801,0.001342079,0.002144726,0.0006707778,0.001296423,0.002045143,0.001759645,0.0115815],"category_scores_gemma":[0.001477244,0.001654084,0.0008287454,0.0009916391,0.0009390089,0.001650988,0.001399415,0.004150569,0.01501249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000536708,"about_ca_system_score_gemma":0.0009594877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006445709,"about_ca_topic_score_gemma":0.001219844,"domain_scores_codex":[0.9987803,0.0001824886,0.0001071868,0.0002953209,0.0004065687,0.0002280666],"domain_scores_gemma":[0.9991232,0.000171201,0.0001652704,0.0002182949,0.0001085659,0.0002134049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004066815,0.00006501249,0.0002372529,0.0003261602,0.00003379111,0.0001716891,0.00008812043,0.0001856175,0.9353912,0.005780288,0.01156878,0.0457454],"study_design_scores_gemma":[0.0001144374,0.0001271101,0.0008315322,0.00004510003,0.00005890696,0.001478946,0.00002344829,0.001079665,0.8820766,0.001192752,0.1129284,0.00004328665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.04953857,0.007670393,0.8823911,0.001527357,0.001311565,0.001344824,0.01050916,0.02425914,0.02144787],"genre_scores_gemma":[0.2691473,0.01211495,0.5499186,0.001584516,0.0003970172,0.001819551,0.03646524,0.008823354,0.1197294],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.0115815,"threshold_uncertainty_score":0.03874403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01266661121289866,"score_gpt":0.2239221039708144,"score_spread":0.2112554927579157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}