{"id":"W4232550090","doi":"10.1002/(sici)1526-968x(200002)26:2<99::aid-gene1>3.3.co;2-2","title":"Cre recombinase: The universal reagent for genome tailoring","year":2000,"lang":"en","type":"article","venue":"genesis","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Recombinase; Genome; Biology; Cre recombinase; Computational biology; Genetics; Gene; Recombination; Transgene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001274643,0.00008750609,0.0000625362,0.00001241851,0.000176397,0.00001523966,0.0001358784,0.00006518963,0.0001592293],"category_scores_gemma":[0.000009850995,0.00006654898,0.00008499037,0.00005223438,0.00003825794,0.000001386449,0.00003186076,0.00002652554,0.0000237915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001003854,"about_ca_system_score_gemma":0.00002619826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002063399,"about_ca_topic_score_gemma":0.000006869393,"domain_scores_codex":[0.9993789,0.00002110505,0.00009688643,0.0002815784,0.00005623243,0.0001653602],"domain_scores_gemma":[0.9995812,0.000003834168,0.00002762106,0.0003058331,0.00004402987,0.0000375351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001747035,0.00004730357,0.0002791062,0.00001371475,0.0000757388,0.000001231945,0.00008265084,0.0008862693,0.9452568,0.00008615995,0.00446077,0.0486355],"study_design_scores_gemma":[0.0002751872,0.0002897683,0.008079533,0.00000224349,0.00003605764,0.00001132019,0.0001394781,0.00004718754,0.1015339,0.00005205742,0.8893829,0.0001503378],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948167,0.001781575,0.0008145376,0.0005249276,0.0001620902,0.0002348904,0.00001340103,0.00001117018,0.001640709],"genre_scores_gemma":[0.9698778,0.001738913,0.0007007822,0.0001458468,0.00071664,0.00003520243,0.00006521198,0.00002366781,0.02669587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8849221,"threshold_uncertainty_score":0.2713788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01266661121289866,"score_gpt":0.2239221039708144,"score_spread":0.2112554927579157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}