{"id":"W4232751552","doi":"10.1210/en.142.11.4693","title":"GATA4 Mediates Activation of the B-Type Natriuretic Peptide Gene Expression in Response to Hemodynamic Stress","year":2001,"lang":"en","type":"article","venue":"Endocrinology","topic":"Cardiac Structural Anomalies and Repair","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Academy of Finland; Medical Research Council Canada; Oulun Yliopisto; Sydäntutkimussäätiö; Foundation for Cardiovascular Research","keywords":"Endocrinology; Internal medicine; Hemodynamics; Natriuretic peptide; GATA4; Activator (genetics); Haemodynamic response; Gene expression; Molecular biology; Gene; Medicine; Biology; Heart failure; Heart rate; Blood pressure; Genetics; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005940091,0.00009788639,0.0002292918,0.0001326315,0.0000341823,0.000002295818,0.00009681998,0.00006267359,0.00007377813],"category_scores_gemma":[0.0003247637,0.00006053348,0.00007966558,0.0002901001,0.00007250169,0.00002586204,0.0001096067,0.0001539444,0.000007359216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006843746,"about_ca_system_score_gemma":0.00004872099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009921162,"about_ca_topic_score_gemma":0.0000316215,"domain_scores_codex":[0.9991206,0.0001166219,0.0002041362,0.0001832882,0.0001406189,0.0002347405],"domain_scores_gemma":[0.9993953,0.0001499039,0.00005997173,0.0002893238,0.00005782114,0.00004763877],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002211996,0.00003256897,0.153328,0.00002214556,0.00001628215,0.0000590874,0.0003117915,0.0001992816,0.8423132,0.00004147092,0.0002188053,0.001245345],"study_design_scores_gemma":[0.0007091665,0.0001674133,0.7357521,0.0000729505,0.00001353214,0.0002033098,0.0002137641,0.00004154533,0.2608045,0.00008199261,0.001877137,0.00006259135],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957901,0.0001829914,0.000008467679,0.003076128,0.0003428487,0.0002767482,0.000006077486,0.00002423621,0.0002924513],"genre_scores_gemma":[0.9985539,0.00009185173,0.000281336,0.0001999752,0.00009312254,0.00000998912,0.00001035341,0.00001011268,0.0007493955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5824242,"threshold_uncertainty_score":0.2468483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009130952413354498,"score_gpt":0.2633733088263556,"score_spread":0.2542423564130011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}