{"id":"W4232976591","doi":"10.1186/preaccept-1482274339133333","title":"MicroRNA-188 suppresses G 1 /S transition by targeting multiple cyclin/CDK complexes","year":2014,"lang":"en","type":"article","venue":"Cell Communication and Signaling","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Nasopharyngeal carcinoma; Cyclin-dependent kinase; microRNA; Cell cycle; Downregulation and upregulation; Cell growth; Cancer research; Cyclin D1; E2F; Biology; Cyclin A; Cell cycle checkpoint; Cell biology; Kinase; Cyclin E; Cell; Gene; Medicine; Internal medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002635999,0.0001158053,0.0001043599,0.00002538108,0.0002362205,0.00005073489,0.0001797849,0.00009418729,0.00003262301],"category_scores_gemma":[0.00005347983,0.0001256424,0.00004737266,0.00004010255,0.00007877406,0.000008880398,0.00007047134,0.00007838201,0.000004764566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007312293,"about_ca_system_score_gemma":0.00001079513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002305954,"about_ca_topic_score_gemma":0.000006569439,"domain_scores_codex":[0.9991657,0.0002123358,0.0002157399,0.0002049532,0.00006818261,0.0001330821],"domain_scores_gemma":[0.9993392,0.0000671776,0.000104581,0.0003526528,0.00007253935,0.00006380866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002413226,0.00004265107,0.0003385161,0.00003459741,0.000009211256,4.065543e-8,0.0001510958,0.0003179534,0.9961343,0.00002291003,0.002511349,0.0004131726],"study_design_scores_gemma":[0.0005533312,0.00003000087,0.0002517919,0.00002437279,0.00001828663,0.000001438754,0.0001558803,0.004150854,0.9540845,0.0001110649,0.04044823,0.0001703077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9730995,0.005383682,0.02065609,0.0001798224,0.00002198231,0.0001362054,0.00002199424,0.00002476725,0.0004759658],"genre_scores_gemma":[0.9941343,0.0003442796,0.00359671,0.0002322693,0.0000522736,0.00001132279,0.001539036,0.00001967295,0.00007012081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04204993,"threshold_uncertainty_score":0.5123547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007831843438440032,"score_gpt":0.2215579568483627,"score_spread":0.2137261134099227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}