{"id":"W4232976591","doi":"10.1186/preaccept-1482274339133333","title":"MicroRNA-188 suppresses G 1 /S transition by targeting multiple cyclin/CDK complexes","year":2014,"lang":"en","type":"article","venue":"Cell Communication and Signaling","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Nasopharyngeal carcinoma; Cyclin-dependent kinase; microRNA; Cell cycle; Downregulation and upregulation; Cell growth; Cancer research; Cyclin D1; E2F; Biology; Cyclin A; Cell cycle checkpoint; Cell biology; Kinase; Cyclin E; Cell; Gene; Medicine; Internal medicine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009422538,0.0002752442,0.0002514518,0.0001948661,0.0001223282,0.0002503726,0.0001345557,0.0001453322,0.0008288042],"category_scores_gemma":[0.0001400667,0.0001321416,0.0001872403,0.00008040236,0.0001593298,0.0001077509,0.0001198769,0.0002269237,0.0003227401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002617725,"about_ca_system_score_gemma":0.0002072834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003693339,"about_ca_topic_score_gemma":0.0007200969,"domain_scores_codex":[0.9999117,0.00001987567,0.000008803136,0.00002052334,0.00002303826,0.00001606385],"domain_scores_gemma":[0.9999517,0.00001054473,0.00001648257,0.000005554727,0.00000637256,0.000009355566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001103343,0.00001644964,0.0002550815,0.00004158059,0.000004063153,0.00004938466,0.000007135736,0.0001061854,0.9961149,0.0001551352,0.0001050842,0.003034763],"study_design_scores_gemma":[0.00001650626,0.0001912804,0.003026262,0.000003508445,0.00001196346,0.0002755055,0.00001008937,0.0009621327,0.989783,0.00003731671,0.005679572,0.000002850323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793721,0.005196195,0.008742389,0.0001958121,0.00007788465,0.00006052829,0.0003432199,0.0003680804,0.005643873],"genre_scores_gemma":[0.9912871,0.001537402,0.004912222,0.00005793043,0.00001594683,0.00003303705,0.0002711657,0.00003491039,0.001850283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008288042,"threshold_uncertainty_score":0.002772629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007831843438440032,"score_gpt":0.2215579568483627,"score_spread":0.2137261134099227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}