{"id":"W4233039575","doi":"10.1021/ol040012f","title":"A Formal Construction of Fasicularin","year":2004,"lang":"en","type":"article","venue":"Organic Letters","topic":"Marine Toxins and Detection Methods","field":"Environmental Science","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Combinatorial chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001067043,0.00004831434,0.00005964314,0.00001625098,0.00003888881,0.000005194061,0.00006093254,0.00002134504,0.002676524],"category_scores_gemma":[0.00001247306,0.00004353743,0.00002983912,0.0001403666,0.00008894937,0.0001189374,0.00006406412,0.00005276547,0.000114072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009922169,"about_ca_system_score_gemma":0.000006397931,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001863359,"about_ca_topic_score_gemma":0.00002598365,"domain_scores_codex":[0.9995718,0.00001451741,0.00009928108,0.00009737826,0.0001103168,0.0001067274],"domain_scores_gemma":[0.9998079,0.000005469132,0.00004284679,0.0001121264,0.000001619715,0.00003002547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000004855845,0.0000132405,0.006447247,0.000002811287,0.000003809084,0.000002413489,0.000102418,0.0002801889,0.9786476,0.0002813819,0.00006653463,0.01414751],"study_design_scores_gemma":[0.0007622846,0.00006240288,0.05035377,0.000004350767,0.00001205571,0.0001014364,0.00005853496,0.00004158625,0.9447476,0.001000545,0.002707118,0.000148304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9182438,9.062123e-7,0.07873291,0.0006441905,0.00009417586,0.00004339978,3.663156e-7,0.00002108593,0.00221916],"genre_scores_gemma":[0.9575734,0.000001058628,0.04176667,0.0006002688,0.00002098552,0.00000148875,5.027327e-7,0.000005432108,0.00003025326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04390652,"threshold_uncertainty_score":0.9982352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005436720240624372,"score_gpt":0.2056818164249976,"score_spread":0.2002450961843732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}