{"id":"W4233052103","doi":"10.1016/j.jalz.2018.06.2511","title":"P4‐107: REGIONAL PATTERNS OF TAU DEPOSITION DRIVEN BY LOCAL AMYLOID ACCUMULATION RECAPITULATE BRAAK STAGES IN AD","year":2018,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill Genome Centre; Douglas Mental Health University Institute; Douglas College; McGill University","funders":"","keywords":"Statistical parametric mapping; Pittsburgh compound B; Amyloidosis; Positron emission tomography; Amyloid (mycology); Pathology; Pathological; Standardized uptake value; Voxel; Medicine; Alzheimer's disease; Neuroscience; Psychology; Disease; Nuclear medicine; Magnetic resonance imaging; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001982673,0.0003548387,0.0004850691,0.0006252662,0.0002134485,0.0004066942,0.0003491317,0.0004575121,0.002010963],"category_scores_gemma":[0.000306786,0.00027506,0.0002477515,0.0003135773,0.0004801411,0.0002824668,0.0002797823,0.0006166679,0.000806033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003586349,"about_ca_system_score_gemma":0.0001785471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002351335,"about_ca_topic_score_gemma":0.002119118,"domain_scores_codex":[0.9998282,0.00002126292,0.000018158,0.00005823969,0.00003986629,0.00003433404],"domain_scores_gemma":[0.9998606,0.00001801362,0.00003369044,0.00002593212,0.00002760352,0.0000339701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001642626,0.0001605423,0.008452447,0.0001078287,0.00004614236,0.001753836,0.0001598251,0.000243325,0.9785833,0.0001534216,0.0004391674,0.008257441],"study_design_scores_gemma":[0.000228644,0.002319227,0.4706637,0.00005529619,0.0002170287,0.01936261,0.0004971368,0.005636252,0.4937635,0.001254065,0.005922721,0.00007986402],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942269,0.0004564341,0.002457219,0.00004477785,0.00001432531,0.00004708027,0.0009790199,0.0001033536,0.001670751],"genre_scores_gemma":[0.9934224,0.000275145,0.002387711,0.00005636701,0.000004923491,0.00009425126,0.001201245,0.0000764857,0.002481314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002351335,"threshold_uncertainty_score":0.006727397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03849661538341114,"score_gpt":0.3347327313309139,"score_spread":0.2962361159475027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}