{"id":"W4233190561","doi":"10.2144/02333st02_11839a","title":"Determination of Methylation Site of DNA-Methyltransferase <i>Nla</i>X by a Hybrid Method","year":2002,"lang":"en","type":"article","venue":"BioTechniques","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Research Council Canada; Lomonosov Moscow State University","keywords":"Uracil-DNA glycosylase; DNA glycosylase; Cytosine; Oligonucleotide; 5-Methylcytosine; DNA methyltransferase; Methyltransferase; DNA; Bisulfite; Methylation; Biochemistry; Uracil; Molecular biology; DNA methylation; Chemistry; Bisulfite sequencing; Biology; Gene; DNA repair; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000415424,0.0001331926,0.0001887614,0.00009552883,0.00002769598,0.00000688265,0.0001053563,0.0001888187,0.00003559623],"category_scores_gemma":[0.00008523848,0.0001349282,0.0001110967,0.000120195,0.00005715508,0.000006993428,0.00003052573,0.00006139198,0.000001009744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008902902,"about_ca_system_score_gemma":0.00001019627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004573255,"about_ca_topic_score_gemma":0.000004300118,"domain_scores_codex":[0.9989625,0.0001425303,0.000365467,0.0002469126,0.0001585609,0.0001240591],"domain_scores_gemma":[0.9993032,0.00003253937,0.0001859215,0.0002919713,0.0001450471,0.00004130675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001769137,0.00007230289,0.0001690392,0.00002587234,0.00001236248,2.758406e-7,0.00004158267,0.000003375674,0.9400039,0.0000243808,0.0003714426,0.05925779],"study_design_scores_gemma":[0.0001799136,0.000397663,0.00009575875,0.00001600806,0.00002992797,0.00000123614,0.000004312383,0.0007747753,0.9889014,0.0003484619,0.009114296,0.0001362215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.383604,0.002683539,0.6127056,0.00005957232,0.00002902333,0.0002125443,0.00009706034,0.00002175735,0.0005869851],"genre_scores_gemma":[0.8952383,0.002006661,0.1023848,0.00002995865,0.00003611263,0.00001624116,0.000145563,0.00001947937,0.000122902],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5116343,"threshold_uncertainty_score":0.5502211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01242345720724644,"score_gpt":0.2742837062827131,"score_spread":0.2618602490754667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}