{"id":"W4233190561","doi":"10.2144/02333st02_11839a","title":"Determination of Methylation Site of DNA-Methyltransferase <i>Nla</i>X by a Hybrid Method","year":2002,"lang":"en","type":"article","venue":"BioTechniques","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Research Council Canada; Lomonosov Moscow State University","keywords":"Uracil-DNA glycosylase; DNA glycosylase; Cytosine; Oligonucleotide; 5-Methylcytosine; DNA methyltransferase; Methyltransferase; DNA; Bisulfite; Methylation; Biochemistry; Uracil; Molecular biology; DNA methylation; Chemistry; Bisulfite sequencing; Biology; Gene; DNA repair; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002920305,0.0004276336,0.0003789075,0.0004596421,0.0002416117,0.0004546928,0.000464508,0.0004927933,0.001485919],"category_scores_gemma":[0.0004578963,0.0004041069,0.0002650468,0.0002253186,0.0002759421,0.0002950274,0.000379796,0.000814584,0.0009114249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000284763,"about_ca_system_score_gemma":0.0001574496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006319496,"about_ca_topic_score_gemma":0.001169566,"domain_scores_codex":[0.9997002,0.0000555148,0.00001771708,0.0001385256,0.00006383568,0.00002420959],"domain_scores_gemma":[0.9996235,0.0001351665,0.00006937976,0.00005423115,0.00006456133,0.00005304991],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004158102,0.000005493179,0.0001614972,0.00002188795,0.000006765043,0.00001398115,0.00001756949,0.00003769487,0.9980488,0.00008702594,0.00001345356,0.001544344],"study_design_scores_gemma":[0.000006302361,0.00006380827,0.001136826,0.000003559785,0.00002051451,0.0001338468,0.00001555746,0.0006402397,0.9961017,0.00005525802,0.001812834,0.000009540991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6984053,0.002623915,0.289558,0.0001810183,0.0001194291,0.0001253566,0.00113602,0.001190172,0.006660836],"genre_scores_gemma":[0.842194,0.001627142,0.1446921,0.00007854364,0.00002785728,0.0001784566,0.001983357,0.000163028,0.009055508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001485919,"threshold_uncertainty_score":0.004970849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01242345720724644,"score_gpt":0.2742837062827131,"score_spread":0.2618602490754667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}