{"id":"W4233825533","doi":"10.4161/cbt.6.3.4165","title":"Clinical Benefit of Antisense Therapy in a Phase III Trial in Patients with CLL","year":2007,"lang":"en","type":"article","venue":"Cancer Biology & Therapy","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Fludarabine; Chronic lymphocytic leukemia; Chemotherapy; Oncology; Internal medicine; Clinical trial; Cancer; Leukemia; Population; Cyclophosphamide","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001494896,0.0008425328,0.001431415,0.0003442531,0.0004483427,0.00132532,0.0003143951,0.001302428,0.004414569],"category_scores_gemma":[0.001348762,0.0002946783,0.0009906386,0.0002647939,0.0005540221,0.0008074905,0.000322012,0.00273055,0.0006989824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000808849,"about_ca_system_score_gemma":0.00106942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005236042,"about_ca_topic_score_gemma":0.0008470967,"domain_scores_codex":[0.9995409,0.0002193982,0.00002563195,0.00006825955,0.00005498835,0.00009087392],"domain_scores_gemma":[0.9992301,0.0001618313,0.000105101,0.00004668064,0.00007960237,0.0003767316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5821586,0.02799339,0.006165837,0.001092836,0.001549453,0.0003931056,0.0005439176,0.00314787,0.08175834,0.001567446,0.02213077,0.2714983],"study_design_scores_gemma":[0.4968203,0.4767342,0.006486991,0.0001342342,0.0004274336,0.0002794961,0.0001195306,0.001594285,0.005164047,0.0007870503,0.01140233,0.00005020604],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9715665,0.0115096,0.001468686,0.004592923,0.001317151,0.002676166,0.001390558,0.0002934945,0.005185068],"genre_scores_gemma":[0.9784733,0.004682045,0.001735944,0.004522158,0.0006315139,0.002771229,0.00183706,0.00004273593,0.00530398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004414569,"threshold_uncertainty_score":0.01476818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05949674630688416,"score_gpt":0.4390387247558386,"score_spread":0.3795419784489544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}