{"id":"W4233925073","doi":"10.1177/120347540500900501","title":"Evaluation of the Effectiveness of Imiquimod and 5-Fluorouracil for the Treatment of Actinic Keratosis: Critical Review and Meta-Analysis of Efficacy Studies","year":2005,"lang":"en","type":"article","venue":"Journal of Cutaneous Medicine and Surgery","topic":"Nonmelanoma Skin Cancer Studies","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mediprobe Research (Canada); Sunnybrook Health Science Centre","funders":"","keywords":"Actinic keratosis; Imiquimod; Medicine; Dermatology; Keratosis; Fluorouracil; Cryotherapy; Photodermatosis; Surgery; Basal cell; Internal medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.03247496,0.002996636,0.02253205,0.00875356,0.0006327619,0.003025198,0.003058309,0.002777078,0.002813203],"category_scores_gemma":[0.062032,0.001793951,0.03220819,0.007039096,0.001011826,0.001816916,0.00113267,0.001628484,0.0002411603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003630196,"about_ca_system_score_gemma":0.002735567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004160626,"about_ca_topic_score_gemma":0.007374438,"domain_scores_codex":[0.9781852,0.01395534,0.004300599,0.001444547,0.001810476,0.0003038275],"domain_scores_gemma":[0.9342325,0.05318424,0.007593886,0.00125435,0.00315423,0.0005807353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.005831812,0.00003824088,0.003409431,0.2114907,0.7665722,0.0001914716,0.00008090755,0.000757414,0.0002595244,0.0001074006,0.0004581269,0.01080277],"study_design_scores_gemma":[0.001272064,0.0004263687,0.002394162,0.008962742,0.9852476,0.0001116698,0.00004308445,0.0002620775,0.0001639021,0.0001536977,0.0009405803,0.00002203216],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006980643,0.9910545,0.0006389504,0.0002075635,0.0001774257,0.0004003158,0.0002667118,0.00002647376,0.0002474867],"genre_scores_gemma":[0.3182669,0.6740575,0.003853183,0.0008724506,0.0004904248,0.001370562,0.0007388367,0.00004589422,0.0003041744],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.977468,"threshold_uncertainty_score":0.1717461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2381540134945921,"score_gpt":0.4380405513174632,"score_spread":0.1998865378228711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}