{"id":"W4234420388","doi":"10.3410/f.1119178.575341","title":"Faculty Opinions recommendation of Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance.","year":2008,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; Terry Fox Foundation; Lucas Foundation; National Cancer Institute; Prostate Cancer Foundation","keywords":"Androgen receptor; Prostate cancer; Exon; Cancer research; Androgen; RNA splicing; Alternative splicing; Receptor; Prostate; Medicine; Internal medicine; Endocrinology; Oncology; Cancer; Biology; Genetics; Gene; Hormone","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001718783,0.0009807093,0.0008758081,0.002451657,0.0004664833,0.001461147,0.001815855,0.001148848,0.04206075],"category_scores_gemma":[0.01087109,0.0003642116,0.0009892277,0.003711549,0.0001980614,0.0006347691,0.0007478238,0.00116075,0.03253592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001191277,"about_ca_system_score_gemma":0.003159032,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01561084,"about_ca_topic_score_gemma":0.04329062,"domain_scores_codex":[0.9985871,0.0002757515,0.0001958964,0.0002518941,0.0005714937,0.0001178404],"domain_scores_gemma":[0.9940561,0.001858025,0.0008076783,0.0009219736,0.001962146,0.000394099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00011498,0.0000244844,0.002464874,0.0004734192,0.00004672852,0.00001904694,0.000008308833,0.0001420409,0.0001707671,0.0002070828,0.9896743,0.006653999],"study_design_scores_gemma":[0.0003219904,0.00003481196,0.02100707,0.0002541037,0.0001328683,0.00009594353,0.00003858551,0.0008272009,0.001292092,0.0004162215,0.9755515,0.00002767491],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"commentary","genre_scores_codex":[0.0009397095,0.0001503591,0.0001636253,0.0003990495,0.0001013227,0.00003560137,0.9946457,0.0002641445,0.003300442],"genre_scores_gemma":[0.00177862,0.0001289925,0.0006557232,0.0001818362,0.00002824987,0.00008245037,0.993099,0.00005499759,0.003990094],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.04206075,"threshold_uncertainty_score":0.1407073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0701607183011582,"score_gpt":0.3808318042698311,"score_spread":0.3106710859686729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}