{"id":"W4234455852","doi":"10.1152/physiolgenomics.00001.2010","title":"Alterations in the proteome of the NHERF1 knockout mouse jejunal brush border membrane vesicles","year":2010,"lang":"en","type":"article","venue":"Physiological Genomics","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; McGill University; Johns Hopkins University","keywords":"Ezrin; PDZ domain; Brush border; Cell biology; Biology; Scaffold protein; Adherens junction; Cytoskeleton; Proteome; Membrane protein; Apical membrane; Villin; Transport protein; Molecular biology; Vesicle; Biochemistry; Cell; Signal transduction; Actin; Membrane; Cadherin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001184681,0.00008620026,0.00008816829,0.00001033602,0.00007429231,0.000009666944,0.0002609307,0.0001106165,0.00002764372],"category_scores_gemma":[0.00002296869,0.00004627121,0.00008230492,0.00006792157,0.0001218395,0.000002775103,0.0000355452,0.0001457302,0.000002685421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003119612,"about_ca_system_score_gemma":0.00002875024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001316445,"about_ca_topic_score_gemma":0.00007371604,"domain_scores_codex":[0.9994375,0.00004790827,0.0001655927,0.0001544101,0.00007146929,0.0001231543],"domain_scores_gemma":[0.9996172,0.000009235011,0.00006157561,0.0002597174,0.00003466131,0.00001762193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000336031,0.0000589282,0.000238017,0.000004877345,0.000006215982,1.142778e-7,0.0001082186,0.000623427,0.9983077,0.0003386731,0.00004302766,0.0002371986],"study_design_scores_gemma":[0.0002396802,0.00008386952,0.09441493,0.000002213553,0.00000695474,0.000001697396,0.00007158116,0.0001758356,0.9003163,0.0006956481,0.003899048,0.00009226605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990063,0.00002705521,0.00008407155,0.0003640743,0.00008028665,0.0002585222,0.00001608477,0.000003806578,0.000159775],"genre_scores_gemma":[0.9990845,0.00002650273,0.0001582191,0.0002205455,0.0002571811,0.00003024956,0.00007015214,0.000006495688,0.0001461165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09799141,"threshold_uncertainty_score":0.1886885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01252986342594252,"score_gpt":0.245053665804186,"score_spread":0.2325238023782435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}