{"id":"W4234455852","doi":"10.1152/physiolgenomics.00001.2010","title":"Alterations in the proteome of the NHERF1 knockout mouse jejunal brush border membrane vesicles","year":2010,"lang":"en","type":"article","venue":"Physiological Genomics","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; McGill University; Johns Hopkins University","keywords":"Ezrin; PDZ domain; Brush border; Cell biology; Biology; Scaffold protein; Adherens junction; Cytoskeleton; Proteome; Membrane protein; Apical membrane; Villin; Transport protein; Molecular biology; Vesicle; Biochemistry; Cell; Signal transduction; Actin; Membrane; Cadherin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001160146,0.0003479705,0.0002767726,0.0004507498,0.0001947574,0.0002958141,0.0001596496,0.0003460991,0.0008214277],"category_scores_gemma":[0.0001329695,0.0002080917,0.000339279,0.0002049514,0.0001790256,0.0002570969,0.0002439103,0.0004565641,0.0003115272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000208415,"about_ca_system_score_gemma":0.0001128354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004400231,"about_ca_topic_score_gemma":0.0003959009,"domain_scores_codex":[0.999859,0.000008530712,0.00001395032,0.00005306039,0.00003975214,0.00002564507],"domain_scores_gemma":[0.9998635,0.00001478164,0.00004744626,0.00001263711,0.00002579417,0.00003581343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007964784,0.000003887699,0.0002356867,0.00002270058,0.000007121569,0.00005551255,0.00001202441,0.0000106061,0.9991346,0.00002814758,0.00001685933,0.0003932298],"study_design_scores_gemma":[0.00001956372,0.0002405432,0.1140942,0.00003434811,0.00009973021,0.001962264,0.0001452642,0.000801823,0.8775583,0.000194281,0.00482951,0.00002023701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923895,0.002040701,0.002526513,0.00009146356,0.00003801422,0.00001531233,0.002195311,0.0000636902,0.0006394915],"genre_scores_gemma":[0.9818548,0.002459386,0.004129251,0.0001395256,0.00002760685,0.00008305726,0.005587859,0.0001052999,0.005613248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008214277,"threshold_uncertainty_score":0.002748013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01252986342594252,"score_gpt":0.245053665804186,"score_spread":0.2325238023782435,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}