{"id":"W4234719559","doi":"10.21203/rs.3.rs-124700/v1","title":"Precision Medicine, Developmental Plasticity and Prevention of Non-Communicable Disease","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research; Raine Medical Research Foundation; Safe Work Australia; University of Notre Dame Australia; Murdoch University; Government of Western Australia; Edith Cowan University; Curtin University of Technology; National Health and Medical Research Council; Women and Infants Research Foundation; Department of Health, Government of Western Australia; Australian Government; Medical Research Council; University of Notre Dame","keywords":"Non-communicable disease; Communicable disease; Disease; Precision medicine; Medicine; Psychology; Environmental health; Neuroscience; Public health; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004914946,0.0005935975,0.001368711,0.001765739,0.0005361451,0.002877104,0.0005563884,0.001799282,0.01231223],"category_scores_gemma":[0.02392386,0.0003514408,0.0006257718,0.002683398,0.001524115,0.001973478,0.001078016,0.001336621,0.001189035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00119976,"about_ca_system_score_gemma":0.001989011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005333604,"about_ca_topic_score_gemma":0.003792936,"domain_scores_codex":[0.997279,0.001688755,0.0000948392,0.0003982594,0.0004288298,0.0001102912],"domain_scores_gemma":[0.9898605,0.007443487,0.0008788271,0.001035199,0.0004954109,0.0002866595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0004747806,0.0001347965,0.05967237,0.001131476,0.00126617,0.0008276586,0.000628497,0.00953747,0.001525811,0.6128094,0.06213477,0.2498568],"study_design_scores_gemma":[0.00006770709,0.00004364616,0.0200749,0.0002613257,0.0001920962,0.0004720551,0.0002024134,0.007179267,0.0005951559,0.9401007,0.0307905,0.00002031988],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1037488,0.138427,0.411602,0.2054681,0.005080692,0.0001682431,0.0163009,0.001820858,0.1173833],"genre_scores_gemma":[0.7916496,0.06308425,0.1010745,0.005084318,0.006001412,0.0002102119,0.002173565,0.0003512831,0.03037092],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01231223,"threshold_uncertainty_score":0.04118854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07162547304963413,"score_gpt":0.4088185609493525,"score_spread":0.3371930878997184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}