{"id":"W4235081779","doi":"10.1172/jci200112346","title":"Tumor-specific immunity and antiangiogenesis generated by a DNA vaccine encoding calreticulin linked to a tumor antigen","year":2001,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":250,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; National Health Research Institutes; National Institutes of Health; University of Alberta; Alexander and Margaret Stewart Trust","keywords":"Calreticulin; DNA vaccination; Cancer research; Antigen; Immunotherapy; Immunology; MHC class I; Biology; Cancer; CD8; Medicine; Immune system; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002688504,0.0004454428,0.0003016278,0.0002790082,0.0000899107,0.0002429142,0.0001803082,0.0006202267,0.001011257],"category_scores_gemma":[0.0001700053,0.0001441008,0.0002911257,0.0001217789,0.0003384189,0.0002465474,0.0002183009,0.001051559,0.0002194031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000211441,"about_ca_system_score_gemma":0.0002709603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001286545,"about_ca_topic_score_gemma":0.0002477983,"domain_scores_codex":[0.9997457,0.00006717083,0.00001891719,0.0000443614,0.00005799308,0.00006581964],"domain_scores_gemma":[0.99989,0.00002432315,0.00003358551,0.00001367271,0.00001002664,0.00002844282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002689267,0.0002717209,0.0002329356,0.00007093695,0.000007837494,0.00004960005,0.00001258908,0.0001753376,0.9947102,0.0002191368,0.00004024568,0.003940506],"study_design_scores_gemma":[0.0001810839,0.003821698,0.003951429,0.00001323327,0.0000325933,0.0005408084,0.00001742954,0.001878193,0.9869351,0.00009217731,0.002531308,0.000005023798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914002,0.001853808,0.004231422,0.0001348526,0.00005411054,0.0001395111,0.0001194787,0.0000705544,0.001995995],"genre_scores_gemma":[0.9941813,0.0006404864,0.003702753,0.00007991586,0.00001851398,0.00008264955,0.0002140233,0.000009832823,0.001070451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001011257,"threshold_uncertainty_score":0.003382981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05023108018379265,"score_gpt":0.3201335877642197,"score_spread":0.2699025075804271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}