{"id":"W4235159110","doi":"10.1182/blood.v126.23.1842.1842","title":"Addition of Cyclophosphamide, on Demand, to Lenalidomide and Corticosteroids in Patients with Relapsed/Refractory Multiple Myeloma, a Retrospective Review of a Single Centre Experience","year":2015,"lang":"en","type":"review","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Lenalidomide; Medicine; Regimen; Multiple myeloma; Internal medicine; Cyclophosphamide; Dexamethasone; Gastroenterology; Progression-free survival; Bortezomib; Progressive disease; Surgery; Median follow-up; Oncology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001213478,0.0002475508,0.000621532,0.001465282,0.0002913164,0.0008356944,0.0005512171,0.0004271271,0.001132855],"category_scores_gemma":[0.003812306,0.0003135866,0.0007329712,0.002337391,0.0003854307,0.0004185419,0.0002804333,0.0003568447,0.0003572212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006815267,"about_ca_system_score_gemma":0.0008655392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002273487,"about_ca_topic_score_gemma":0.003016618,"domain_scores_codex":[0.9987472,0.0003609254,0.000372109,0.0002061838,0.000242695,0.00007089921],"domain_scores_gemma":[0.9966583,0.0009597202,0.001688598,0.0001456736,0.0003691367,0.000178591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001871736,0.0002972478,0.8800846,0.004142506,0.0009815794,0.01818111,0.000870938,0.000231851,0.003330391,0.0001265961,0.002156865,0.08772461],"study_design_scores_gemma":[0.0002899016,0.00316663,0.8875886,0.001934348,0.001857462,0.08619127,0.001880678,0.0003801404,0.002172516,0.00005681953,0.0144279,0.00005381689],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9132318,0.08328544,0.0004245007,0.0002254982,0.00004861965,0.0001728913,0.0006956899,0.00001809654,0.001897329],"genre_scores_gemma":[0.9678307,0.0303111,0.0005695057,0.0003096464,0.0001002698,0.00006265145,0.0005751809,0.00001185754,0.0002291306],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002273487,"threshold_uncertainty_score":0.006417572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02754775931199357,"score_gpt":0.3001757576348941,"score_spread":0.2726279983229006,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}