{"id":"W4235227157","doi":"10.1136/ijgc-2019-igcs.310","title":"310 Chemotherapy reduces PAR glycohydrolase (PARG) expression in high-grade serous ovarian cancer patients","year":2019,"lang":"fr","type":"article","venue":"International Journal of Gynecological Cancer","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University; Jewish General Hospital","funders":"","keywords":"Immunohistochemistry; Ovarian cancer; Chemotherapy; Serous fluid; Cancer; Cancer research; Medicine; Internal medicine; Oncology; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005608337,0.00009123793,0.0001613441,0.00009990612,0.00008720703,0.000194969,0.00006362356,0.0001366056,0.001920572],"category_scores_gemma":[0.0002463068,0.0000801508,0.0001155762,0.000137508,0.00007529113,0.00008607572,0.00008245123,0.0002405151,0.0002208435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001480447,"about_ca_system_score_gemma":0.0001688922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004860117,"about_ca_topic_score_gemma":0.0008851893,"domain_scores_codex":[0.9999566,0.000009183176,0.00000329097,0.000007639995,0.00001101501,0.00001224498],"domain_scores_gemma":[0.9999498,0.00001099699,0.00001668222,0.000002842905,0.000006321623,0.00001329922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.02802073,0.001368761,0.1590227,0.0007328919,0.0004117823,0.0007840535,0.0001780026,0.002187648,0.5216554,0.0003830622,0.01067325,0.2745816],"study_design_scores_gemma":[0.002653799,0.01638608,0.8061472,0.0001172979,0.000543237,0.003001638,0.0003869435,0.004190052,0.1319249,0.000456936,0.03415218,0.0000397971],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948304,0.00311763,0.0001556526,0.0002066868,0.00004236193,0.00002135683,0.0002105616,0.00004357014,0.001371742],"genre_scores_gemma":[0.9978006,0.0008734504,0.0001706346,0.00009604753,0.00001095176,0.00001152784,0.0002787017,0.000002713832,0.0007552613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001920572,"threshold_uncertainty_score":0.006424963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01873908139536862,"score_gpt":0.3266469672862661,"score_spread":0.3079078858908975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}