{"id":"W4235387577","doi":"10.1002/ange.200453769","title":"Pseudodynamic Combinatorial Libraries: A Receptor‐Assisted Approach for Drug Discovery","year":2004,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Chemistry; Dipeptide; Stereochemistry; Combinatorial chemistry; Peptide; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001083335,0.0002140322,0.0002582068,0.00002619742,0.0001083559,0.00009502659,0.000257447,0.0001808066,0.00001692161],"category_scores_gemma":[0.0001110795,0.000190025,0.0003210707,0.0001372074,0.000100991,0.00001569822,0.0001035245,0.00008103773,0.000003809793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004321008,"about_ca_system_score_gemma":0.00008509853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002963917,"about_ca_topic_score_gemma":0.000004876041,"domain_scores_codex":[0.9988489,0.00001256911,0.0002235597,0.0004796107,0.0001347364,0.0003006149],"domain_scores_gemma":[0.999378,0.00002298982,0.00009070802,0.0003518406,0.00005152338,0.000104961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001302889,0.0002204352,0.000111239,0.00004774774,0.0001364463,4.720359e-7,0.00003405872,0.00001946559,0.9931879,0.0006074077,0.00535009,0.0001544598],"study_design_scores_gemma":[0.001311325,0.00004739968,0.00002897559,0.00001589254,0.00006723941,0.000002746729,0.00008856528,0.00000843212,0.9790192,0.0009372019,0.01819683,0.0002761597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844005,0.001124781,0.008604924,0.0005325488,0.0002467304,0.0003415,0.0001626022,0.00005390727,0.004532561],"genre_scores_gemma":[0.9914653,0.0001100765,0.004557203,0.0001596368,0.000685882,0.0001078204,0.001426017,0.00004054402,0.001447554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01416865,"threshold_uncertainty_score":0.7748996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009428987097387867,"score_gpt":0.22124228701913,"score_spread":0.2118132999217421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}