{"id":"W4235426531","doi":"10.1182/blood.v106.11.355.355","title":"CD28-Mediated Regulation of Multiple Myeloma Cell Proliferation and Survival.","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Stromal cell; Multiple myeloma; Bone marrow; CD28; Cancer research; Plasma cell; CD86; Biology; Monoclonal gammopathy of undetermined significance; CD80; T cell; Immunology; Medicine; CD40; Monoclonal; Antibody; In vitro; Cytotoxic T cell; Monoclonal antibody; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008863294,0.0001932555,0.0001355088,0.0001648564,0.000146199,0.0002038065,0.0001236425,0.000147916,0.001964069],"category_scores_gemma":[0.0001076056,0.00006349494,0.0001199586,0.00008727375,0.0001300549,0.00008753221,0.0002110458,0.0003932782,0.000434842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003115227,"about_ca_system_score_gemma":0.0001707713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005514545,"about_ca_topic_score_gemma":0.0008869531,"domain_scores_codex":[0.9998833,0.00002371746,0.000005150558,0.00001849594,0.00003219523,0.00003720347],"domain_scores_gemma":[0.9999188,0.00002278265,0.00001361103,0.000008334956,0.00001392974,0.00002258005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003250828,0.00006844952,0.0002736574,0.00007328527,0.000004755395,0.00008181873,0.00001531163,0.000150195,0.9926843,0.0002484207,0.0001900301,0.005884708],"study_design_scores_gemma":[0.0000384051,0.0004097111,0.005379452,0.000006323642,0.000008538305,0.0002282448,0.00002589705,0.001913619,0.9859999,0.0001250862,0.00586246,0.00000232583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816327,0.008832203,0.002659159,0.0001661654,0.00007287322,0.0000423463,0.0005003624,0.0001249197,0.005969151],"genre_scores_gemma":[0.9944359,0.0008823333,0.000867105,0.00003017394,0.0000120726,0.00002921743,0.0003079406,0.000007732388,0.003427468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001964069,"threshold_uncertainty_score":0.006570458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01814111498117671,"score_gpt":0.265237578060888,"score_spread":0.2470964630797113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}