{"id":"W4235465754","doi":"10.1038/bjc.2013.828","title":"Galectin-1 has potential prognostic significance and is implicated in clear cell renal cell carcinoma progression through the HIF/mTOR signaling axis","year":2014,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Galectins and Cancer Biology","field":"Immunology and Microbiology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; York University; St. Michael's Hospital","funders":"Kidney Foundation of Canada; Prostate Cancer Canada; Canadian Institutes of Health Research; Government of Ontario; Cancer Research Society","keywords":"PI3K/AKT/mTOR pathway; Cancer research; Clear cell renal cell carcinoma; Protein kinase B; Biology; Renal cell carcinoma; Metastasis; Galectin-1; Galectin-3; Targeted therapy; Signal transduction; Cancer; Medicine; Pathology; Internal medicine; Immunology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002291241,0.0003651422,0.000253349,0.0006471727,0.0001905259,0.0006565433,0.0001870312,0.0002859914,0.002159751],"category_scores_gemma":[0.0003745345,0.0001199341,0.0002840466,0.0005901305,0.0002446752,0.0002109653,0.0002419589,0.0004988301,0.0003265098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004664306,"about_ca_system_score_gemma":0.0002033009,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006137409,"about_ca_topic_score_gemma":0.0005379436,"domain_scores_codex":[0.9998647,0.00003577005,0.000008121274,0.0000251892,0.00004056913,0.0000256402],"domain_scores_gemma":[0.9997408,0.00003222153,0.0001323603,0.000009070855,0.00004063609,0.00004492517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003507999,0.0003039563,0.2850603,0.0008990135,0.0005003611,0.0007268976,0.0001088187,0.001058336,0.636852,0.000965195,0.003187597,0.06682955],"study_design_scores_gemma":[0.0001286666,0.0009229848,0.7965089,0.00006569903,0.0004418873,0.003347109,0.0001257926,0.005073218,0.1793333,0.0009078689,0.01309801,0.00004646526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9803635,0.01420162,0.001840417,0.0006157547,0.00005398335,0.00003324308,0.001172729,0.00008353493,0.001635262],"genre_scores_gemma":[0.9957477,0.001989075,0.0006368883,0.00006265014,0.00002531722,0.00001584832,0.0008577175,0.000007089391,0.0006577063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002159751,"threshold_uncertainty_score":0.007225037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01103890196749072,"score_gpt":0.2425393994721007,"score_spread":0.2315004975046099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}