{"id":"W4235556888","doi":"10.3410/f.726084365.793518748","title":"Faculty Opinions recommendation of Conversion of graded phosphorylation into switch-like nuclear translocation via autoregulatory mechanisms in ERK signalling.","year":2016,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Genetics, Bioinformatics, and Biomedical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Phosphorylation; MAPK/ERK pathway; Chromosomal translocation; Signalling; Cell biology; Chemistry; Kinase; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001236164,0.002561584,0.001692407,0.002367597,0.0006250907,0.002457915,0.002575492,0.002837409,0.04570485],"category_scores_gemma":[0.005898803,0.0006269891,0.002188923,0.003319459,0.0003565149,0.00145179,0.001533229,0.001654765,0.05086792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00149467,"about_ca_system_score_gemma":0.002540426,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0195403,"about_ca_topic_score_gemma":0.05217965,"domain_scores_codex":[0.9987636,0.0001595505,0.0001212949,0.0004957999,0.0002965026,0.0001632774],"domain_scores_gemma":[0.9979649,0.0005925602,0.0003034507,0.0004759455,0.0003874444,0.0002756838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003693958,0.00005137538,0.004393864,0.001989409,0.0001675037,0.00005523472,0.00001877774,0.0007316145,0.000729612,0.0005326168,0.9857262,0.005234403],"study_design_scores_gemma":[0.0009249215,0.00006899824,0.01969737,0.0006752018,0.0002865402,0.0002279516,0.00005933658,0.002580726,0.002915171,0.002762274,0.9697298,0.0000717356],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.0004263465,0.0002394136,0.0001180494,0.0001098443,0.00003996411,0.000009902553,0.9976744,0.0005657786,0.0008163042],"genre_scores_gemma":[0.001236349,0.0001311278,0.0003356806,0.00009427783,0.00001000049,0.00003227467,0.9972342,0.00006927772,0.0008568419],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.04570485,"threshold_uncertainty_score":0.152898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01893979035733131,"score_gpt":0.3105154207828736,"score_spread":0.2915756304255423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}