{"id":"W4235803847","doi":"10.1111/epi.14557","title":"Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). I. Drugs in preclinical and early clinical development","year":2018,"lang":"en","type":"article","venue":"Epilepsia","topic":"Epilepsy research and treatment","field":"Medicine","cited_by":127,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"UCB Pharma; Teva Pharmaceutical Industries; Medical Research Council; Agenzia Italiana del Farmaco, Ministero della Salute; Greenwich Biosciences; Sun Pharma; Stockholms Läns Landsting; Eisai; King's College London; Robarts Research Institute; Epilepsy Research UK; Ministero della Salute; Northwestern University; Ontario Brain Institute; GlaxoSmithKline; LivaNova; Wellcome Trust; National Institute for Health and Care Research; European Commission; U.S. Department of Defense; GW Pharmaceuticals; Sanofi; Upsher-Smith; Canadian Institutes of Health Research; Ministry of Defense; Mylan","keywords":"Antiepileptic drug; Medicine; Epilepsy; Pharmacology; Drug development; Drug discovery; partial seizures; Neuroscience; Drug; Bioinformatics; Psychiatry; Psychology; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003330596,0.002042766,0.0009148263,0.003720526,0.0005643218,0.003797786,0.001164391,0.002048041,0.02058866],"category_scores_gemma":[0.001651902,0.000499476,0.0009044144,0.003087027,0.0003125828,0.002765463,0.001503808,0.002616013,0.01385167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00178457,"about_ca_system_score_gemma":0.00505613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001621182,"about_ca_topic_score_gemma":0.002759786,"domain_scores_codex":[0.9980313,0.0002135702,0.0002433372,0.0001768981,0.001029835,0.0003050002],"domain_scores_gemma":[0.9983316,0.0001677971,0.000275564,0.00004698855,0.0008350704,0.0003430153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003164609,0.0003870913,0.0005357306,0.007649654,0.00004590512,0.0002269877,0.00008483115,0.0007156316,0.01097461,0.004833284,0.3742548,0.599975],"study_design_scores_gemma":[0.00001665854,0.0002636245,0.0008860534,0.000848608,0.00002494938,0.0001232195,0.00003061513,0.00005385522,0.001611938,0.0004442937,0.9956836,0.00001263887],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003299983,0.7987099,0.00469336,0.01653329,0.02401692,0.001196496,0.006013984,0.0004474009,0.1450887],"genre_scores_gemma":[0.01019665,0.8164439,0.007175174,0.008567889,0.009552062,0.0009006368,0.01260013,0.0001957839,0.1343677],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02058866,"threshold_uncertainty_score":0.06887597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06348653406164707,"score_gpt":0.3780976594893309,"score_spread":0.3146111254276839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}